Biography
Awards & Honors
Award | Conferred By | Date |
---|---|---|
R03 | NIDDK | 2022/2024 |
K23 | NIDDK | 2017/2023 |
K Scholars Team Science Award | UCSF | 2017/2018 |
UCSF Hellman Research Award | UCSF | 2016/2018 |
RAP Pilot Award for Junior Investigators | UCSF | 2016/2017 |
Liver Center Flex Funds | UCSF | 2015/2016 |
Liver Center Pilot/Feasibility Research Award | UCSF Liver Center | 2014/2015 |
Sheila Sherlock Career Development Research Award | AASLD | 2013/2015 |
Advanced Hepatology Fellowship Award | AASLD | 2012/2013 |
Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
UCSF | Transplant Hepatology Fellowship | 2013 | |
UCSF | Gastroenterology Fellowship | 2012 | |
UCSF | M.A.S. in Clinical Research | Graduate Division (Advance Training in Clinical Research) | 2012 |
University of Pennsylvania | Internal Medicine Residency | 2009 | |
UCSF | M.D. | School of Medicine | 2006 |
Vassar College | BA | 2002 |
Board Certifications
American Board of Internal Medicine
American Board of Internal Medicine - Gastroenterology
American Board of Internal Medicine - Transplant Hepatology
Clinical Expertise
Alcoholic Liver Disease
Autoimmune Hepatitis
Cirrhosis
Drug-Induced Hepatitis
Fulminant Hepatic Failure
Hemochromatosis
Hepatitis B
Hepatitis C
Hepatocellular Carcinoma (Liver Cancer)
Liver Transplantation
Living Donor Liver Transplantation
Nonalcoholic Fatty Liver Disease
Polycystic Liver Disease
Primary Biliary Cirrhosis
Primary Sclerosing Cholangitis
Clinical Trials
- Bicalutamide Therapy in Young Women With NAFLD and PCOS (NCT05979389)Related Conditions: Nonalcoholic Fatty Liver Disease, Polycystic Ovary Syndrome, Liver Disease| Start Date: | End Date:
- Global Linerixibat Itch Study of Efficacy and Safety in Primary Biliary Cholangitis (PBC) (GLISTEN) (NCT04950127)Related Conditions: Pruritus, Primary Biliary Cholangitis, Cirrhosis| Start Date: | End Date:
- Spironolactone Therapy In Young Women With NASH (NCT03576755)Related Conditions: Nonalcoholic Steatohepatitis, Steatohepatitis, Liver Disease, Nonalcoholic Fatty Liver Disease| Start Date: | End Date:
- Saroglitazar Magnesium 4 mg in the Treatment of NAFLD in Women With PCOS (EVIDENCES VII) (NCT03617263)Related Conditions: Liver Disease, Nonalcoholic Fatty Liver Disease, Polycystic Ovary Syndrome| Start Date: | End Date:
Foreign Languages Spoken
Program Affiliations
UCSF Liver Center
Grants and Funding
- Influence of Androgens on Tissue-Specific Lipid Metabolites and Liver Injury in Young Women with NAFLD | NIDDK | 2022-03-15 - 2024-03-15 | Role: Principle Investigator
- Androgens and Nonalcoholic Steatohepatitis: The Role of Male Sex Hormones in Women with NASH | NIH | 2017-07-10 - 2023-06-30 | Role: Principal Investigator
Research Narrative
My research program is focused on the role of sex hormones on liver injury in women, including the effects of reproductive aging, pregnancy, and androgens. I have a specific interest in young women with the hyperandrogenic condition known as Polycystic Ovarian Syndrome as these women are at high risk for developing Non Alcoholic Fatty Liver Disease and early onset liver scarring. Within the transplant setting I also study sex differences in waitlist and post transplant outcomes.
Research Interests
Women with chronic liver disease
Non invasive measures of liver fibrosis
Gender differences in liver transplant outcomes
Publications
- Contraception in patients with liver disease and liver transplant.| | View in PubMed
- How I Approach Hepatocellular Adenomas in Hormonally Distinct Populations: Time to Think Outside the (Contraceptive Pill) Box.| | View in PubMed
- Introduction: Pregnancy and liver disease.| | View in PubMed
- Antimullerian Hormone, a Marker of Ovarian Reserve, Is Protective Against Presence and Severity of NASH in Premenopausal Women.| | View in PubMed
- Parental leave, childcare policies, and workplace bias for hepatology professionals: A national survey.| | View in PubMed
- Family planning and donor type: Unrecognized benefits of living donor liver transplantation?| | View in PubMed
- Sex differences in chronic liver disease and benign liver lesions.| | View in PubMed
- Mo1530 OUTCOMES IN WOMEN WITH CHRONIC LIVER DISEASE UNDERGOING INFERTILITY TREATMENT.| | View in PubMed
- Sa1609 POLYCYSTIC OVARY SYNDROME INCREASES FIBROSIS SEVERITY IN YOUNG WOMEN WITH NAFLD.| | View in PubMed
- Prevalence of nonalcoholic fatty liver disease increased with type 2 diabetes mellitus in overweight/obese youth with polycystic ovary syndrome.| | View in PubMed
- Reproductive health and liver disease: a patient-friendly summary of the 2021 AASLD guidance.| | View in PubMed
- Letter to the Editor: Influence of maternal NAFLD on infant weight-the real precursor to NAFLD in offspring?| | View in PubMed
- The key role of hepatology providers in optimizing reproductive care in patients with liver disease: A call to action.| | View in PubMed
- Influence of progestin-only hormonal use on hepatocellular adenomas: A retrospective cohort study.| | View in PubMed
- Now you see it, now you don't: Estrogen exposure and obesity effects on HCA development and regression.| | View in PubMed
- Awarding additional MELD points to the shortest waitlist candidates improves sex disparity in access to liver transplant in the United States.| | View in PubMed
- Polycystic ovary syndrome is associated with nonalcoholic steatohepatitis in women of reproductive age.| | View in PubMed
- Reply.| | View in PubMed
- On the Importance of Safe Access to Reproductive Options for Adolescents and Women With Liver Disease.| | View in PubMed
- Su1406: POLCYSTIC OVARY SYNDROME (PCOS) INCREASES RISK OF NASH AMONG REPRODUCTIVE-AGED WOMEN WITH NAFLD: A US POPULATION-BASED STUDY.| | View in PubMed
- Associations of NAFLD with circulating ceramides and impaired glycemia.| | View in PubMed
- Abstract P139: Changes In Sex Hormones In Premenopausal Black And White Women Associated With Childbearing: The Cardia Women’s Study.| | View in PubMed
- Pregnancies With Cirrhosis Are Rising and Associated With Adverse Maternal and Perinatal Outcomes.| | View in PubMed
- Outcomes of pregnancy in autoimmune hepatitis: A population-based study.| | View in PubMed
- Untangling the Influence of Sex Hormones on Nonalcoholic Fatty Liver Disease in Women.| | View in PubMed
- Pregnancy Outcomes After Living Liver Donation: A Multi-Institutional Study.| | View in PubMed
- Sa362 REPRODUCTIVE HEALTH CHARACTERISTICS IN PRE-MENOPAUSAL WOMEN WITH NAFLD.| | View in PubMed
- Adherence to pregnancy hepatitis B care guidelines in women and infants in the United States and evaluation of two interventions to improve care: A multicentre hospital-based study.| | View in PubMed
- NAFLD Cirrhosis Is Rising Among Childbearing Women and Is the Most Common Cause of Cirrhosis in Pregnancy.| | View in PubMed
- Reproductive Health and Liver Disease: Practice Guidance by the American Association for the Study of Liver Diseases.| | View in PubMed
- Reply to: "Intrahepatic cholestasis of pregnancy: An under recognised complication of maternal NAFLD?"| | View in PubMed
- Testosterone is Associated With Nonalcoholic Steatohepatitis and Fibrosis in Premenopausal Women With NAFLD.| | View in PubMed
- Family Planning in Liver Transplant: Patient and Provider Knowledge and Practices.| | View in PubMed
- Outcomes of Pregnant Women With Cirrhosis and Their Infants in a Population-Based Study.| | View in PubMed
- SAT147 Increased risk of perinatal complications in women with cirrhosis: a population-based matched cohort study.| | View in PubMed
- Reproductive Health and Nonalcoholic Fatty Liver Disease in Women: Considerations Across the Reproductive Lifespan.| | View in PubMed
- Non-alcoholic fatty liver disease in pregnancy is associated with adverse maternal and perinatal outcomes.| | View in PubMed
- Pregnancy in Liver Transplantation.| | View in PubMed
- 1004 PREGNANCIES WITH CIRRHOSIS ARE RISING AND ASSOCIATED WITH ADVERSE MATERNAL AND FETAL OUTCOMES.| | View in PubMed
- Shorter Height Is Associated With Lower Probability of Liver Transplantation in Patients With Hepatocellular Carcinoma.| | View in PubMed
- Low Testosterone Is Associated With Nonalcoholic Steatohepatitis and Fibrosis Severity in Men.| | View in PubMed
- NAFLD in women: Unique pathways, biomarkers and therapeutic opportunities.| | View in PubMed
- Polycystic ovary syndrome (PCOS) is associated with NASH severity and advanced fibrosis.| | View in PubMed
- Deficiencies in Reproductive Health Counseling in Liver Transplant Patients [2H].| | View in PubMed
- Sa1623 – Low Testosterone is Associated with Nash and Fibrosis Severity in Men with Nafld.| | View in PubMed
- Sex Hormone-Binding Globulin Levels in Young Men Are Associated With Nonalcoholic Fatty Liver Disease in Midlife.| | View in PubMed
- Testosterone Levels in Women: Implications for Fatty Liver and Beyond.| | View in PubMed
- Noninvasive Tests for Prognosticating Outcomes in Patients With Chronic Liver Disease in Pregnancy: Ready for Prime Time?| | View in PubMed
- Sex hormone levels by presence and severity of cirrhosis in women with chronic hepatitis C virus infection.| | View in PubMed
- Longer lactation duration is associated with decreased prevalence of non-alcoholic fatty liver disease in women.| | View in PubMed
- Chronic Hepatitis B in Pregnancy.| | View in PubMed
- Racial and Ethnic Differences in Graft Loss Among Female Liver Transplant Recipients.| | View in PubMed
- Reproductive health in women following abdominal organ transplant.| | View in PubMed
- The Association of Hispanic Ethnicity with Nonalcoholic Fatty Liver Disease in Polycystic Ovary Syndrome.| | View in PubMed
- Use of a hepatitis C virus (HCV) RNA-positive donor in a treated HCV RNA-negative liver transplant recipient.| | View in PubMed
- Sex-based disparities in delisting for being "too sick" for liver transplantation.| | View in PubMed
- Acetaminophen-induced Acute Liver Failure Is More Common and More Severe in Women.| | View in PubMed
- Moderate Alcohol Use Is Not Associated With Fibrosis Progression in Human Immunodeficiency Virus/Hepatitis C Virus-Coinfected Women: A Prospective Cohort Study.| | View in PubMed
- Perinatal programming of adolescent nonalcoholic fatty liver disease: A case for gender inequality?| | View in PubMed
- Reproductive Aging and Hepatic Fibrosis Progression in Human Immunodeficiency Virus/Hepatitis C Virus-Coinfected Women.| | View in PubMed
- Testosterone Levels in Pre-Menopausal Women are Associated With Nonalcoholic Fatty Liver Disease in Midlife.| | View in PubMed
- Aggressive non-alcoholic steatohepatitis following rapid weight loss and/or malnutrition.| | View in PubMed
- Sex differences in the association of HIV infection with hepatic steatosis.| | View in PubMed
- Increased hepatocellular carcinoma recurrence in women compared to men with high alpha fetoprotein at liver transplant.| | View in PubMed
- Association of Hepatitis C Virus Infection With CD4/CD8 Ratio in HIV-Positive Women.| | View in PubMed
- Marijuana Use Is Not Associated With Progression to Advanced Liver Fibrosis in HIV/Hepatitis C Virus-coinfected Women.| | View in PubMed
- 352 Sex Differences in Acetaminophen-Induced Acute Liver Injury and Acute Liver Failure.| | View in PubMed
- Association between markers of non-alcoholic fatty liver disease and glucose tolerance in polycystic ovarian syndrome population.| | View in PubMed
- Intention to treat outcome of T1 hepatocellular carcinoma with the "wait and not ablate" approach until meeting T2 criteria for liver transplant listing.| | View in PubMed
- PS073 Light to Moderate Alcohol Use is not Associated with Long-Term Progression of Liver Fibrosis in Hiv Hcv Coinfected Women.| | View in PubMed
- PS077 Sex Differences in Acetaminophen-Induced Acute Liver Injury and Acute Liver Failure.| | View in PubMed
- Association of IFNL3 and IFNL4 polymorphisms with liver-related mortality in a multiracial cohort of HIV/HCV-coinfected women.| | View in PubMed
- Outcomes in liver transplantation: does sex matter?| | View in PubMed
- Ending vertical transmission of hepatitis B: the third trimester intervention.| | View in PubMed
- Characteristics and management of patients with chronic hepatitis B in an integrated care setting.| | View in PubMed
- Factors associated with outcomes and response to therapy in patients with infiltrative hepatocellular carcinoma.| | View in PubMed
- Racial/ethnic differences in spontaneous HCV clearance in HIV infected and uninfected women.| | View in PubMed
- Lower liver-related death in African-American women with human immunodeficiency virus/hepatitis C virus coinfection, compared to Caucasian and Hispanic women.| | View in PubMed
- 466 Hepatitis B Treatment in a California Managed Care Population: A Retrospective Analysis of Treatment and Monitoring Practices.| | View in PubMed
- Hepatocellular carcinoma screening practices and impact on survival among hepatitis B-infected Asian Americans.| | View in PubMed
- Chapter 32 Hepatitis virus infections.| | View in PubMed
- Proton-pump inhibitor use and the risk for community-acquired pneumonia.| | View in PubMed
- Chronic statin therapy and the risk of colorectal cancer.| | View in PubMed
- Presentation and management of acute fistulization of a foregut duplication cyst.| | View in PubMed