Biography
Dr. Perito treats all types of pediatric liver, pancreatic, and gastrointestinal diseases, in all ages from newborns through young adults. Her clinical care and research focus on optimizing long-term outcomes for children with liver and pancreatic diseases.
She is Medical Director of UCSF's Pediatric Liver Center and Associate Medical Director of UCSF's multi-disciplinary Pediatric Liver Transplant team with expertise in the care of children with pediatric liver disease before and in the long-term after transplant. Dr. Perito leads epidemiologic research focused on improving access to transplant, organ allocation, and waitlist outcomes for children awaiting liver transplant. She is Co-Chair the Starzl Network for Excellence in Pediatric Transplantation and helps lead their efforts to improve the efficacy and reduce the burden of immunosuppression for children after liver transplant. She also advocates for children nationally as Chair of UNOS' Pediatric Transplantation Committee (2022-2024), Chair of the Society for Pediatric Liver Transplant's Advocacy Committee (2020-2023), and a member of AASLD's Pediatric Special Interest Group.
She is also co-director of UCSF's Pediatric Pancreas Program. She lead's UCSF's work in NIH-sponsored multi-center trials including the INSPPIRE study on acute recurrent and chronic pancreatitis in children and adolescents. Her work in chronic pancreatitis includes research on chronic pain management, opioid use, and outcomes after TPIAT.
Before coming to UCSF, Dr. Perito did her pediatrics training and medical school at Columbia University in New York City.
Awards & Honors
Award | Conferred By | Date |
---|---|---|
Fellow's Leadership and Advocacy Group Faculty Mentor Award | UCSF | 2015 |
AGA Emmet B. Keeffe Award in Translational or Clinical Research in Liver Disease | UCSF | 2013/2014 |
UCSF CTSI-SOS Early Career Investigators Pilot Award | UCSF | 2013/2014 |
UCSF Liver Center Pilot/Feasibility Award | UCSF | 2013/2014 |
Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
University of California, San Francisco | Diversity, Equity, and Inclusion Champion Training | 10/2020 | |
University of California, San Francisco | M.A.S. in Clinical Research | Graduate Division (Advance Training in Clinical Research) | 2012 |
Columbia University College of Physicians and Surgeons | M.D. | Medicine | 2006 |
Harvard University | B.A. | History and Science | 2001 |
Board Certifications
American Board of Pediatrics, General Pediatrics
American Board of Pediatrics, Pediatric Gastroenterology Subspecialty
American Board of Pediatrics, Pediatric Transplant Hepatology Subspecialty
Clinical Expertise
Gastroesophageal Reflux Disease (Pediatric)
Inflammatory Bowel Disease
Intestinal Failure
Short Bowel Syndrome
Liver Transplant (Pediatric)
Chronic Pancreatitis
Pancreatic Insufficiency
Metabolic Liver Disease
Fatty Liver Disease (Nonalcoholic Steatohepatitis)
Program Affiliations
Intestinal Rehabilitation and Transplantation Program
Liver Transplant Program
Inflammatory bowel disease (IBD) Program
Grants and Funding
- PARTNER ADVance: Patient-Centered Research in Pediatric Transplant, Engaging Families and Recipients - Young Adult and Adolescent Advisors | Patient-Centered Outcomes Research Institute | 2024-03-01 - 2026-02-28 | Role: Co-Project Lead
- INSPPIRE: A Longitudinal Cohort Study of Pediatric Chronic Pancreatitis to Predict Clinical Course and Identify Disease Modifiers | NIH | 2015-09-28 - 2025-06-30 | Role: Co-Investigator
- SNEPT and SPLIT implementation of a QoL measure in pediatric transplant recipients | NIH | 2021-08-01 - 2024-07-31 | Role: Co-Investigator
- Improving Medication Adherence in adolescents who had a Liver Transplant: iMALT | NIH | 2018-09-20 - 2023-08-31 | Role: Co-Investigator
- PARTNER: Patient-Centered Research in Pediatric Transplant: Engaging Families and Recipients | Patient-Centered Outcomes Research Institute | 2020-02-01 - 2023-05-01 | Role: Co-Project Lead
- Metabolic Syndrome after Pediatric Liver Transplant: Causes and Consequences | NIH | 2014-09-15 - 2019-06-30 | Role: Principal Investigator
- Improving Medication Adherence in children who had a Liver Transplant: iMALT | NIH | 2016-09-14 - 2018-06-30 | Role: Co-Investigator
- Prevalence & correlates of post-traumatic stress in adolescent solid organ transplant recipients | NIH/Clinical Trial in Organ Transplantation | 2016-03-01 - 2018-02-28 | Role: Site PI
- Non-standard exception requests and their impact in pediatric liver transplant: A mixed-methods analysis of United Network for Organ Sharing data, 2009-2014 | UCSF Department of Pediatrics | 2016-07-01 - 2017-07-01 | Role: Principal Investigator
Research Narrative
Dr. Perito is a clinical and translational researcher whose interests focus on long-term outcomes for children with liver and pancreatic diseases. She is currently leading an NIH-sponsored study about post-transplant metabolic syndrome in pediatric liver transplant recipients. She is also active in epidemiologic research about organ allocation for children awaiting research. She is an investigator in the INSPPIRE consortium, which studies chronic pancreatitis in children and adolescents, as well as multi-center studies on liver transplant outcomes.
Research Interests
Pediatric Liver Transplantation
Long-Term Outcomes After Liver Transplantation
Chronic Pancreatitis
Pancreatic Insufficiency
Metabolic Liver Disease
Non-Alcoholic Fatty Liver Disease
Pediatric Gastroenterology
Epidemiology
Publications
- Impact of Elevated Serum Triglycerides on Children with Acute Recurrent or Chronic Pancreatitis from INSPPIRE-2.| | PubMed
- Pancreatic Enzyme Use Reduces Pancreatitis Frequency in Children With Acute Recurrent or Chronic Pancreatitis: A Report From INSPPIRE.| | PubMed
- Availability and utilization of endoscopic retrograde cholangiopancreatography at children's hospitals.| | PubMed
- Index admission cholecystectomy for biliary acute pancreatitis or choledocholithiasis reduces 30-day readmission rates in children.| | PubMed
- Oral vancomycin is associated with improved inflammatory bowel disease clinical outcomes in primary sclerosing cholangitis-associated inflammatory bowel disease (PSC-IBD): A matched analysis from the Paediatric PSC Consortium.| | PubMed
- Food insecurity is a risk factor for metabolic dysfunction-associated steatotic liver disease in Latinx children.| | PubMed
- Omicron Infections in Vaccinated Pediatric Solid Organ Transplant Recipients.| | PubMed
- Patient-centered research in pediatric transplant: Engaging families and recipients.| | PubMed
- Anti-spike antibody durability after SARS-CoV-2 vaccination in adolescent solid organ transplant recipients.| | PubMed
- Impact of early immunosuppression on pediatric liver transplant outcomes within 1 year.| | PubMed
- Freedom isn't free: Assessing the risks and benefits of steroid-free immunosuppression regimens in pediatric liver transplantation in a real-world setting.| | PubMed
- Association of state Medicaid expansion policies with pediatric liver transplant outcomes.| | PubMed
- Bone health in children with recurrent and chronic pancreatitis: A multi-center cross sectional analysis.| | PubMed
- Implementation of a National Liver Review Board for exception requests in the United States: A 2-year monitoring report.| | PubMed
- Bone health in children with recurrent and chronic pancreatitis: A multi-center cross sectional analysis.| | UCSF Research Profile
- Pediatric Drug-Associated Pancreatitis Reveals Concomitant Risk Factors and Poor Reliability of Causality Scoring: Report From INSPPIRE.| | PubMed
- Mapping children by ALT 4-5 years after liver transplant: Potential individual and population applications.| | PubMed
- Novel autoantibody targets identified in patients with autoimmune hepatitis (AIH) by PhIP-Seq reveals pathogenic insights.| | PubMed
- Pediatric Medical Traumatic Stress and Trauma-Informed Care in Pediatric Chronic Illness: A Healthcare Provider Survey.| | PubMed
- Advancing the Field of Pediatric Liver Transplantation: Urgent Action Items Identified During the 2022 Society of Pediatric Liver Transplantation Meeting.| | PubMed
- Prevalence of nonalcoholic fatty liver disease increased with type 2 diabetes mellitus in overweight/obese youth with polycystic ovary syndrome.| | PubMed
- Financial, policy, and ethical barriers to the expansion of living donor liver transplant: Meeting report from a living donor liver transplant consensus conference.| | PubMed
- Medical traumatic stress in cystic fibrosis: A qualitative analysis.| | PubMed
- Association of Lifetime Exposure to Glyphosate and Aminomethylphosphonic Acid (AMPA) with Liver Inflammation and Metabolic Syndrome at Young Adulthood: Findings from the CHAMACOS Study.| | PubMed
- Immunosuppression after pediatric liver transplant: The parents' perspective.| | PubMed
- Center use of technical variant grafts varies widely and impacts pediatric liver transplant waitlist and recipient outcomes in the United States.| | PubMed
- Waitlist mortality in pediatric liver transplantation: The goal is zero.| | PubMed
- Utility of illness symptoms for predicting COVID-19 infections in children.| | PubMed
- Feasibility of using a patient-reported outcome measure into clinical practice following pediatric liver transplantation: The Starzl Network experience.| | PubMed
- Editorial: Optimizing Outcomes for Children Requires Ensuring Access to Living: Donor and Split Liver Transplants.| | PubMed
- Analysis of INSPPIRE-2 Cohort: Risk Factors and Disease Burden in Children With Acute Recurrent or Chronic Pancreatitis.| | PubMed
- Clinical Trials in Pancreatitis: Opportunities and Challenges in the Design and Conduct of Patient-Focused Clinical Trials in Recurrent Acute and Chronic Pancreatitis: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop.| | PubMed
- Pediatric Medical Traumatic Stress in Inflammatory Bowel Disease, Pancreatitis, and Cystic Fibrosis.| | PubMed
- Antibody response to three SARS-CoV-2 mRNA vaccines in adolescent solid organ transplant recipients.| | PubMed
- Graft Fibrosis Over 10 to 15 Years in Pediatric Liver Transplant Recipients: Multicenter Study of Paired, Longitudinal Surveillance Biopsies.| | PubMed
- Interobserver Agreement for CT and MRI Findings of Chronic Pancreatitis in Children: A Multicenter Ancillary Study Under the INSPPIRE Consortium.| | PubMed
- Health-Related Quality of Life in Pediatric Acute Recurrent or Chronic Pancreatitis: Association With Biopsychosocial Risk Factors.| | PubMed
- Outpatient Pain Management in Children With Chronic Pancreatitis: A Scoping Systematic Review.| | PubMed
- We Asked the Experts: Toward Personalized Immunosuppression for Liver Transplant Recipients.| | PubMed
- Not everything that counts can be counted: Tracking long-term outcomes in pediatric liver transplant recipients.| | PubMed
- 271: Loss of control, shifts in illness identity, and perceived vulnerability underlie traumatic illness–related experiences in patients with cystic fibrosis.| | UCSF Research Profile
- Baby Steps: Understanding Allograft Fibrosis in Pediatric Liver Transplantation.| | PubMed
- Vascular Complications in Pediatric Pancreatitis: A Case Series.| | PubMed
- Antibody response to 2-dose SARS-CoV-2 mRNA vaccination in pediatric solid organ transplant recipients.| | PubMed
- Recurrence of Primary Sclerosing Cholangitis After Liver Transplant in Children: An International Observational Study.| | PubMed
- Liver transplant in children and adults with cystic fibrosis: Impact of growth failure and nutritional status.| | PubMed
- Complications of chronic pancreatitis in children.| | PubMed
- Optimizing COVID-19 Symptom Screening in the Pediatric Population.| | UCSF Research Profile
- Liver simulated allocation model does not effectively predict organ offer decisions for pediatric liver transplant candidates.| | PubMed
- Non-operative management of biliary complications after Liver Transplantation in pediatric patients: A 30-year experience.| | PubMed
- 577 INTER-RATER AGREEMENT ON IMAGING FINDINGS OF CHRONIC PANCREATITIS IN A PEDIATRIC COHORT.| | UCSF Research Profile
- Donor-Specific and Auto-Antibodies in Pediatric Liver Transplant: When Are They Important? What Do They Mean?| | PubMed
- Efficacy and Safety of Immunosuppression Withdrawal in Pediatric Liver Transplant Recipients: Moving Toward Personalized Management.| | PubMed
- Save the Children: The Ethical Argument for Preferential Priority to Minors in Deceased Donor Liver Allocation.| | PubMed
- A Learning Health System for Pediatric Liver Transplant: The Starzl Network for Excellence in Pediatric Transplantation.| | PubMed
- Oral Vancomycin, Ursodeoxycholic Acid, or No Therapy for Pediatric Primary Sclerosing Cholangitis: A Matched Analysis.| | PubMed
- To Juice or Not to Juice: Fatty Liver Repercussions for Infants.| | PubMed
- Dialogs in the assessment of neonatal cholestatic liver disease.| | PubMed
- The Sclerosing Cholangitis Outcomes in Pediatrics (SCOPE) Index: A Prognostic Tool for Children.| | PubMed
- Predicting Severity in Acute Pancreatitis in Children: What Can a Quantitative Score Add to Clinical Judgement?| | PubMed
- Vedolizumab Therapy in Children With Primary Sclerosing Cholangitis: Data From the Pediatric Primary Sclerosing Cholangitis Consortium.| | PubMed
- Family Planning in Liver Transplant: Patient and Provider Knowledge and Practices.| | PubMed
- Impact of Acuity Circles on Outcomes for Pediatric Liver Transplant Candidates.| | PubMed
- Clinical and Practice Variations in Pediatric Acute Recurrent or Chronic Pancreatitis: Report From the INSPPIRE Study.| | PubMed
- Improving the predictive ability of the pediatric end-stage liver disease score for young children awaiting liver transplant.| | PubMed
- Mo1901 CHILDREN WITH INFLAMMATORY BOWEL DISEASE EXPERIENCE HIGH RATES OF TRAUMA SECONDARY TO MEDICAL TREATMENT.| | UCSF Research Profile
- Colorectal Dysplasia and Cancer in Pediatric-Onset Ulcerative Colitis Associated With Primary Sclerosing Cholangitis.| | PubMed
- Pediatric chronic pancreatitis without prior acute or acute recurrent pancreatitis: A report from the INSPPIRE consortium.| | PubMed
- Factors Associated With Frequent Opioid Use in Children With Acute Recurrent and Chronic Pancreatitis.| | PubMed
- Split liver transplantation is utilized infrequently and concentrated at few transplant centers in the United States.| | PubMed
- Web-based cognitive-behavioral intervention for pain in pediatric acute recurrent and chronic pancreatitis: Protocol of a multicenter randomized controlled trial from the study of chronic pancreatitis, diabetes and pancreatic cancer (CPDPC).| | PubMed
- Diabetes Mellitus in Children with Acute Recurrent and Chronic Pancreatitis: Data From the INternational Study Group of Pediatric Pancreatitis: In Search for a CuRE Cohort.| | PubMed
- Impact of the Pediatric End-Stage Liver Disease (PELD) growth failure thresholds on mortality among pediatric liver transplant candidates.| | PubMed
- Acute Recurrent and Chronic Pancreatitis as Initial Manifestations of Cystic Fibrosis and Cystic Fibrosis Transmembrane Conductance Regulator-Related Disorders.| | PubMed
- Risk Factors for Rapid Progression From Acute Recurrent to Chronic Pancreatitis in Children: Report From INSPPIRE.| | PubMed
- A learning health network for pediatric liver transplantation: Inaugural meeting report from the Starzl Network for Excellence in Pediatric Transplantation.| | PubMed
- Pancreas Divisum in Pediatric Acute Recurrent and Chronic Pancreatitis: Report From INSPPIRE.| | PubMed
- Deficiencies in Reproductive Health Counseling in Liver Transplant Patients [2H].| | UCSF Research Profile
- Chronic Pancreatitis: Pediatric and Adult Cohorts Show Similarities in Disease Progress Despite Different Risk Factors.| | PubMed
- The Impact of Increased Allocation Priority for Children Awaiting Liver Transplant: A Liver Simulated Allocation Model (LSAM) Analysis.| | PubMed
- Treating Biliary Atresia: The Challenge Continues.| | PubMed
- Ursodeoxycholic Acid Therapy in Pediatric Primary Sclerosing Cholangitis: Predictors of Gamma Glutamyltransferase Normalization and Favorable Clinical Course.| | PubMed
- Split Liver Transplantation and Pediatric Waitlist Mortality in the United States: Potential for Improvement.| | PubMed
- Posttransplant biopsy risk for stable long-term pediatric liver transplant recipients: 451 percutaneous biopsies from two multicenter immunosuppression withdrawal trials.| | PubMed
- Editorial.| | UCSF Research Profile
- Center variation in screening for and management of metabolic syndrome in pediatric liver transplant recipients: A survey of SPLIT centers.| | PubMed
- Diet and Exercise in Pediatric Liver Transplant Recipients: Behaviors and Association With Metabolic Syndrome.| | PubMed
- Weight Gain Trajectory Predicts Long-term Overweight and Obesity After Pediatric Liver Transplant.| | PubMed
- Functional status at listing predicts waitlist and posttransplant mortality in pediatric liver transplant candidates.| | PubMed
- INternational Study Group of Pediatric Pancreatitis: In Search for a CuRE Cohort Study: Design and Rationale for INSPPIRE 2 From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer.| | PubMed
- Impact of Obesity on Pediatric Acute Recurrent and Chronic Pancreatitis.| | PubMed
- Nonalcoholic Liver Disease in Children and Adolescents.| | PubMed
- Recommendations for Diagnosis and Management of Autoimmune Pancreatitis in Childhood: Consensus From INSPPIRE.| | PubMed
- Bisphenol a increases risk for presumed non-alcoholic fatty liver disease in Hispanic adolescents in NHANES 2003-2010.| | PubMed
- Subclinical Atherosclerosis in Pediatric Liver Transplant Recipients: Carotid and Aorta Intima-Media Thickness and Their Predictors.| | PubMed
- Association Between Cytokines and Liver Histology in Children with Nonalcoholic Fatty Liver Disease.| | PubMed
- Hepatic steatosis after pediatric liver transplant.| | PubMed
- Autoimmune Pancreatitis in Children: Characteristic Features, Diagnosis, and Management.| | PubMed
- Reply.| | PubMed
- Relief for Young Children With Severe Chronic Pancreatitis.| | PubMed
- Justifying Nonstandard Exception Requests for Pediatric Liver Transplant Candidates: An Analysis of Narratives Submitted to the United Network for Organ Sharing, 2009-2014.| | PubMed
- Prediabetes in Pediatric Recipients of Liver Transplant: Mechanism and Risk Factors.| | PubMed
- De novo inflammatory bowel disease after pediatric kidney or liver transplant.| | PubMed
- Ultrasound elastography: is there a shear wave speed cutoff for pediatric liver fibrosis and inflammation?| | PubMed
- Novel plasma biomarkers associated with liver disease severity in adults with nonalcoholic fatty liver disease.| | PubMed
- Complications of Endoscopic Retrograde Cholangiopancreatography in Pediatric Patients; A Systematic Literature Review and Meta-Analysis.| | PubMed
- The Utility of Nuclear Medicine Scans for Diagnosing Pediatric Biliary Dyskinesia Remains Unclear.| | PubMed
- Nonstandard Exception Requests Impact Outcomes for Pediatric Liver Transplant Candidates.| | PubMed
- Metabolic Syndrome Components After Pediatric Liver Transplantation: Prevalence and the Impact of Obesity and Immunosuppression.| | PubMed
- Under Utilization of Pancreas Transplants in Cystic Fibrosis Recipients in the United Network Organ Sharing (UNOS) Data 1987-2014.| | PubMed
- Posttransplant metabolic syndrome in the withdrawal of immunosuppression in Pediatric Liver Transplant Recipients (WISP-R) pilot trial.| | PubMed
- Liver Disease in Children, 4th Edition. Frederick J. Suchy, Ronald J. Sokol, and William F. Balistreri, editors. 752 pp. $215. New York, New York, Cambridge University Press, 2014. ISBN: 9781107013797. Web address for ordering: www.cambridge.org.| | UCSF Research Profile
- Delineating definitions and risk factors for metabolic syndrome after pediatric liver transplantation.| | PubMed
- Tu1838 Hepatic Steatosis in Pediatric Liver Transplant Recipients: Single-Center Review of Post-Transplant Liver Biopsies.| | UCSF Research Profile
- Liver in Systemic Disease.| | UCSF Research Profile
- Pediatric liver transplantation for urea cycle disorders and organic acidemias: United Network for Organ Sharing data for 2002-2012.| | PubMed
- Targeted hepatic sonography during clinic visits for detection of fatty liver in overweight children: a pilot study.| | PubMed
- Dietary treatment of nonalcoholic steatohepatitis.| | PubMed
- Posttransplant metabolic syndrome in children and adolescents after liver transplantation: a systematic review.| | PubMed
- Impact of the donor body mass index on the survival of pediatric liver transplant recipients and post-transplant obesity.| | PubMed
- 703 Impact of Donor BMI on Survival and Post-Transplant Obesity in Pediatric Liver Transplant Recipients.| | UCSF Research Profile
- Targeted MRI contrast agents for pediatric hepatobiliary disease.| | PubMed
- Solitary rectal ulcer syndrome in children and adolescents.| | PubMed
- Overweight and obesity in pediatric liver transplant recipients: prevalence and predictors before and after transplant, United Network for Organ Sharing Data, 1987-2010.| | PubMed
- Gastric mucosal damage from ingestion of 3 button cell batteries.| | PubMed
- Obesity prevention, screening, and treatment: practices of pediatric providers since the 2007 expert committee recommendations.| | PubMed