University of California San Francisco

Gottschalk
Alexander R. Gottschalk, MD, PhD

Professor of Radiation Oncology
Director, CyberKnife Radiosurgery Program
Department of Radiation Oncology

Address

1600 Divisadero, #H1014
San Francisco, CA 94115
United States

Email: [email protected]
Fax: 415-353-9883

Biography

I am involved with the Urologic, Thoracic, Orthopedic and Gastrointestinal Oncology programs at UCSF. I spend 4 days per week providing clinical coverage for the above programs program. On average, I see 6 new patient consultations per week and 15 patients on treatment. I am responsible for patient simulations, treatment planning, supervision of external-beam radiation therapy, on-treatment visits, and follow-up visits. In addition, I am involved in the brachytherapy, intra-operative radiation therapy and stereotactic body radiotherapy programs. I attend tumor boards for GU, Thoracic, GI, orthopedic oncology programs and at the Veterans Administration Hospital. I work very closely with radiation oncology residents and medical students in all the above activities. I am the Director of the CyberKnife Radiosurgery Program at UCSF and proctor other faculty in this area. As Vice Chair of clinical services I over see clinical operations at the Mount Zion site, and over see the site directors at both the Parnassus Mission Bay and Washington Hospital.

Awards & Honors

Award Conferred By Date
Commitment to Patient Care Award UCSF 2012/2013
Lifetime Teaching Award UCSF 2012/2013
Educator of the Year UCSF 2009/2010

Education

Institution Degree Dept or School End Date
University of Chicago M.D. School of Medicine 1996

Board Certifications

American Board of Radiology

Clinical Expertise

Brain and Spinal Tumors
CyberKnife Irradiation for Lung and Skull Base
Esophageal Cancer
Intensity-modulated radiation therapy (IMRT)
Sarcoma
Stereotactic Lung Radiotherapy (SBRT)
Non-Small Cell Lung Cancer
Small-Cell Lung Cancer
External-beam Radiation
Bronchioloalveolar Carcinoma (BAC)

Clinical Trials

  1. Radiation Therapy in Treating Patients With Prostate Cancer (NCT01434290)
    Related Conditions: Prostate Cancer, Cancer, General, Radiation Toxicity, Sexual Dysfunction| Start Date: | End Date:
  2. Stereotactic Body Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer (NCT00750269)
    Related Conditions: Lung Cancer, Non-Small Cell Lung Cancer, Lung Tumor| Start Date: | End Date:

Program Affiliations

Thoracic Oncology Program
Department of Radiation Oncology
Helen Diller FamilyComprehensive Cancer Center
Sarcoma Program

 

Research Narrative

Dr. Gottschalk is involved in a number of clinical research projects. First, he has studied several methods of image-guided radiotherapy (IGRT), including, ultrasound, electronic portal imagining using gold seed fiducial markers and megavoltage cone-beam CT (MVCBCT). His research is one of the first to evaluate prostate bed motion in patients undergoing radiotherapy after prostatectomy. Dr. Gottschalk has investigated the use of MVCBCT for dose calculation and re-calculation as well as a novel high quality, low dose, imaging beam line. The dose re-calculation can be use for dose guided radiation therapy (DGRT).

Second, using the Radiation Oncology clinical database, Dr. Gottschalk has studied: the effectiveness of intraoperative radiation therapy (IORT) in the management of extremity sarcomas and renal cell carcinoma recurrences, permanent seed brachytherapy and high dose-rate brachytherapy (HDR) for the treatment of prostate cancer both as primary therapy and as salvage after radiation failures.

Third, he has been involved as a co-investigator in three trials: a Phase 2, Single-Center, Open-Label phase I/II study to evaluate safety and efficacy and Safety in patients who have resectable esophageal cancer and are treated with neoadjuvant cisplatin, irinotecan (CPT-11), ZD1839 (IRESSA®), and radiotherapy followed by surgical resection; a phase II study of radiation therapy, paclitaxel poliglumex and carboplatin in stage III non-small cell lung cancer; and a phase I/II open-label dose escalation study of anti-CTLA4 antibody with radiation for metastatic hormone refractory prostate cancer.

 Forth, Dr. Gottschalk is involved with several RTOG (Radiation Therapy Oncology Group) studies. These have included several prostate cancer trials that investigate: high-dose vs standard-dose readiation for intermediate-risk prostate cancer; brachytherapy vs external-beam radiation plus brachytherapy for intermediate-risk prostate cancer; and standard fractionation vs hypofractionation for low-risk prostate cancer. Finally, as Director of the CyberKnife Radiosurgery Program Dr. Gottschalk oversees several of the stereotactic body radiosugery (SBRT) trials for lung and prostate cancer. He has a particular interest in the use of CyberKnife SBRT for the treatment of prostate cancer, kidney cancer, and lung cancer.

Research Interests

  • Radiation in combination with chemotherapy and targeted agents
  • Image-guided and adaptive radiation therapy
  • Radiation sensitizers and protectors

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 155
  1. Deep match: A zero-shot framework for improved fiducial-free respiratory motion tracking.
    Xu D, Descovich M, Liu H, Lao Y, Gottschalk AR, Sheng K| | View in PubMed
  2. Structure-function analysis suggests that the photoreceptor LITE-1 is a light-activated ion channel.
    Hanson SM, Scholüke J, Liewald J, Sharma R, Ruse C, Engel M, Schüler C, Klaus A, Arghittu S, Baumbach F, Seidenthal M, Dill H, Hummer G, Gottschalk A| | View in PubMed
  3. All-optical closed-loop voltage clamp for precise control of muscles and neurons in live animals.
    Bergs ACF, Liewald JF, Rodriguez-Rozada S, Liu Q, Wirt C, Bessel A, Zeitzschel N, Durmaz H, Nozownik A, Dill H, Jospin M, Vierock J, Bargmann CI, Hegemann P, Wiegert JS, Gottschalk A| | View in PubMed
  4. Rapid and reversible optogenetic silencing of synaptic transmission by clustering of synaptic vesicles.
    Vettkötter D, Schneider M, Goulden BD, Dill H, Liewald J, Zeiler S, Guldan J, Ates YA, Watanabe S, Gottschalk A| | View in PubMed
  5. WormRuler: A software to track body length used to characterize a super red-shifted channelrhodopsin in Caenorhabditis elegans.
    Seidenthal M, Vettkötter D, Gottschalk A| | View in PubMed
  6. Addition of Enzalutamide to Leuprolide and Definitive Radiation Therapy Is Tolerable and Effective in High-Risk Localized or Regional Nonmetastatic Prostate Cancer: Results From a Phase 2 Trial.
    Shee K, de la Calle CM, Chang AJ, Wong AC, Feng FY, Gottschalk AR, Carroll PR, Nguyen HG| | View in PubMed
  7. Microbial Rhodopsin Optogenetic Tools: Application for Analyses of Synaptic Transmission and of Neuronal Network Activity in Behavior.
    Bergs A, Henss T, Glock C, Nagpal J, Gottschalk A| | View in PubMed
  8. Photoactivated Adenylyl Cyclases as Optogenetic Modulators of Neuronal Activity.
    Henss T, Schneider M, Vettkötter D, Costa WS, Liewald JF, Gottschalk A| | View in PubMed
  9. BiPOLES is an optogenetic tool developed for bidirectional dual-color control of neurons.
    Vierock J, Rodriguez-Rozada S, Dieter A, Pieper F, Sims R, Tenedini F, Bergs ACF, Bendifallah I, Zhou F, Zeitzschel N, Ahlbeck J, Augustin S, Sauter K, Papagiakoumou E, Gottschalk A, Soba P, Emiliani V, Engel AK, Hegemann P, Wiegert JS| | View in PubMed
  10. Optogenetic tools for manipulation of cyclic nucleotides functionally coupled to cyclic nucleotide-gated channels.
    Henß T, Nagpal J, Gao S, Scheib U, Pieragnolo A, Hirschhäuser A, Schneider-Warme F, Hegemann P, Nagel G, Gottschalk A| | View in PubMed
  11. Synapsin Is Required for Dense Core Vesicle Capture and cAMP-Dependent Neuropeptide Release.
    Yu SC, Liewald JF, Shao J, Steuer Costa W, Gottschalk A| | View in PubMed
  12. Stereotactic Body Radiation Therapy and High-Dose-Rate Brachytherapy Boost in Combination With Intensity Modulated Radiation Therapy for Localized Prostate Cancer: A Single-Institution Propensity Score Matched Analysis.
    Chen WC, Li Y, Lazar A, Altun A, Descovich M, Nano T, Ziemer B, Sudhyadhom A, Cunha A, Thomas H, Gottschalk A, Hsu IC, Roach M| | View in PubMed
  13. Evaluation of a National Comprehensive Cancer Network Guidelines-Based Decision Support Tool in Patients With Non-Small Cell Lung Cancer: A Nonrandomized Clinical Trial.
    Wu SY, Lazar AA, Gubens MA, Blakely CM, Gottschalk AR, Jablons DM, Jahan TM, Wang VEH, Dunbar TL, Wong ML, Chan JW, Guthrie W, Belkora J, Yom SS| | View in PubMed
  14. Context-dependent operation of neural circuits underlies a navigation behavior in Caenorhabditis elegans.
    Ikeda M, Nakano S, Giles AC, Xu L, Costa WS, Gottschalk A, Mori I| | View in PubMed
  15. Stereotactic Body Radiation Therapy of Adrenal Metastases: A Pooled Meta-Analysis and Systematic Review of 39 Studies with 1006 Patients.
    Chen WC, Baal JD, Baal U, Pai J, Gottschalk A, Boreta L, Braunstein SE, Raleigh DR| | View in PubMed
  16. Epidermal Growth Factor Signaling Promotes Sleep through a Combined Series and Parallel Neural Circuit.
    Konietzka J, Fritz M, Spiri S, McWhirter R, Leha A, Palumbos S, Costa WS, Oranth A, Gottschalk A, Miller DM, Hajnal A, Bringmann H| | View in PubMed
  17. Rhodopsin-based voltage imaging tools for use in muscles and neurons of Caenorhabditis elegans.
    Azimi Hashemi N, Bergs ACF, Schüler C, Scheiwe AR, Steuer Costa W, Bach M, Liewald JF, Gottschalk A| | View in PubMed
  18. Using a Robust and Sensitive GFP-Based cGMP Sensor for Real-Time Imaging in Intact Caenorhabditis elegans.
    Woldemariam S, Nagpal J, Hill T, Li J, Schneider MW, Shankar R, Futey M, Varshney A, Ali N, Mitchell J, Andersen K, Barsi-Rhyne B, Tran A, Costa WS, Krzyzanowski MC, Yu YV, Brueggemann C, Hamilton OS, Ferkey DM, VanHoven M, Sengupta P, Gottschalk A, L'Etoile N| | View in PubMed
  19. Dedicated Diagnostic Radiology/Radiation Oncology Rounds: Added Value Beyond Traditional Tumor Boards.
    Kallianos KG, Muhoozi BN, Gottschalk A, Yom SS, Chan JW, Henry TS, Elicker BM, Ordovas KG, Naeger DM| | View in PubMed
  20. A Photoactivatable Botulinum Neurotoxin for Inducible Control of Neurotransmission.
    Liu Q, Sinnen BL, Boxer EE, Schneider MW, Grybko MJ, Buchta WC, Gibson ES, Wysoczynski CL, Ford CP, Gottschalk A, Aoto J, Tucker CL, Kennedy MJ| | View in PubMed
  21. Impact of Staging 68Ga-PSMA-11 PET Scans on Radiation Treatment Plansin Patients With Prostate Cancer.
    Wu SY, Boreta L, Shinohara K, Nguyen H, Gottschalk AR, Hsu IC, Roach M, Westphalen AC, Feng FY, Carroll PR, Chang AJ, Hope TA| | View in PubMed
  22. Food Sensation Modulates Locomotion by Dopamine and Neuropeptide Signaling in a Distributed Neuronal Network.
    Oranth A, Schultheis C, Tolstenkov O, Erbguth K, Nagpal J, Hain D, Brauner M, Wabnig S, Steuer Costa W, McWhirter RD, Zels S, Palumbos S, Miller Iii DM, Beets I, Gottschalk A| | View in PubMed
  23. Expanding the Optogenetics Toolkit by Topological Inversion of Rhodopsins.
    Brown J, Behnam R, Coddington L, Tervo DGR, Martin K, Proskurin M, Kuleshova E, Park J, Phillips J, Bergs ACF, Gottschalk A, Dudman JT, Karpova AY| | View in PubMed
  24. Functionally asymmetric motor neurons contribute to coordinating locomotion of Caenorhabditis elegans.
    Tolstenkov O, Van der Auwera P, Steuer Costa W, Bazhanova O, Gemeinhardt TM, Bergs AC, Gottschalk A| | View in PubMed
  25. Phase I study of dose escalation to dominant intraprostatic lesions using high-dose-rate brachytherapy.
    Chapman CH, Braunstein SE, Pouliot J, Noworolski SM, Weinberg V, Cunha A, Kurhanewicz J, Gottschalk AR, Roach MI, Hsu IC| | View in PubMed
  26. Endophilin A and B Join Forces With Clathrin to Mediate Synaptic Vesicle Recycling in Caenorhabditis elegans.
    Yu SC, Jánosi B, Liewald JF, Wabnig S, Gottschalk A| | View in PubMed
  27. Influence of respiratory motion management technique on radiation pneumonitis risk with robotic stereotactic body radiation therapy.
    Chapman CH, McGuinness C, Gottschalk AR, Yom SS, Garsa AA, Anwar M, Braunstein SE, Sudhyadhom A, Keall P, Descovich M| | View in PubMed
  28. Rhodopsin optogenetic toolbox v2.0 for light-sensitive excitation and inhibition in Caenorhabditis elegans.
    Bergs A, Schultheis C, Fischer E, Tsunoda SP, Erbguth K, Husson SJ, Govorunova E, Spudich JL, Nagel G, Gottschalk A, Liewald JF| | View in PubMed
  29. An optogenetic arrhythmia model to study catecholaminergic polymorphic ventricular tachycardia mutations.
    Fischer E, Gottschalk A, Schüler C| | View in PubMed
  30. ACR Appropriateness Criteria for external beam radiation therapy treatment planning for clinically localized prostate cancer, part II of II.
    Zaorsky NG, Showalter TN, Ezzell GA, Nguyen PL, Assimos DG, D'Amico AV, Gottschalk AR, Gustafson GS, Keole SR, Liauw SL, Lloyd S, McLaughlin PW, Movsas B, Prestidge BR, Taira AV, Vapiwala N, Davis BJ| | View in PubMed
  31. ACR Appropriateness Criteria® Locally Advanced, High-Risk Prostate Cancer.
    McLaughlin PW, Liss AL, Nguyen PL, Assimos DG, D'Amico AV, Gottschalk AR, Gustafson GS, Keole SR, Liauw SL, Lloyd S, Movsas B, Prestidge BR, Showalter TN, Taira AV, Vapiwala N, Davis BJ, Expert Panel on Radiation OncologyProstate| | View in PubMed
  32. Respiration-Induced Intraorgan Deformation of the Liver: Implications for Treatment Planning in Patients Treated With Fiducial Tracking.
    Paulsson AK, Yom SS, Anwar M, Pinnaduwage D, Sudhyadhom A, Gottschalk AR, Chang AJ, Descovich M| | View in PubMed
  33. ACR appropriateness criteria: Permanent source brachytherapy for prostate cancer.
    Davis BJ, Taira AV, Nguyen PL, Assimos DG, D'Amico AV, Gottschalk AR, Gustafson GS, Keole SR, Liauw SL, Lloyd S, McLaughlin PW, Movsas B, Prestidge BR, Showalter TN, Vapiwala N| | View in PubMed
  34. ACR Appropriateness Criteria® external beam radiation therapy treatment planning for clinically localized prostate cancer, part I of II.
    Expert Panel on Radiation Oncology-Prostate:, Zaorsky NG, Showalter TN, Ezzell GA, Nguyen PL, Assimos DG, D'Amico AV, Gottschalk AR, Gustafson GS, Keole SR, Liauw SL, Lloyd S, McLaughlin PW, Movsas B, Prestidge BR, Taira AV, Vapiwala N, Davis BJ| | View in PubMed
  35. Correction: Endoscopic Gold Fiducial Marker Placement into the Bladder Wall to Optimize Radiotherapy Targeting for Bladder-Preserving Management of Muscle-Invasive Bladder Cancer: Feasibility and Initial Outcomes.
    Garcia MM, Gottschalk AR, Brajtbord J, Konety BR, Meng MV, Roach M, Carroll PR| | View in PubMed
  36. Hybrid minimally invasive Ivor Lewis esophagectomy after neoadjuvant chemoradiation yields excellent long-term survival outcomes with minimal morbidity.
    Woodard GA, Crockard JC, Clary-Macy C, Zoon-Besselink CT, Jones K, Korn WM, Ko AH, Gottschalk AR, Rogers SJ, Jablons DM| | View in PubMed
  37. Photoswitchable diacylglycerols enable optical control of protein kinase C.
    Frank JA, Yushchenko DA, Hodson DJ, Lipstein N, Nagpal J, Rutter GA, Rhee JS, Gottschalk A, Brose N, Schultz C, Trauner D| | View in PubMed
  38. Receiver operating curves and dose-volume analysis of late toxicity with stereotactic body radiation therapy for prostate cancer.
    Zhang L, Johnson J, Gottschalk AR, Chang AJ, Hsu IC, Roach M, Seymour ZA| | View in PubMed
  39. Interfraction Anatomical Variability Can Lead to Significantly Increased Rectal Dose for Patients Undergoing Stereotactic Body Radiotherapy for Prostate Cancer.
    Wahl M, Descovich M, Shugard E, Pinnaduwage D, Sudhyadhom A, Chang A, Roach M, Gottschalk A, Chen J| | View in PubMed
  40. Long-term Outcomes Following Radiation Therapy For Prostate Cancer Patients With Lymph Node Metastases at Diagnosis Treated With and Without Surgery.
    Crehange G, Izaguirre A, Weinberg V, Hsu CC, Gottschalk AR, Hsu IC, Shinohara K, Carroll P, Roach M| | View in PubMed
  41. An Evaluation of Robotic and Conventional IMRT for Prostate Cancer: Potential for Dose Escalation.
    Pinnaduwage DS, Descovich M, Lometti MW, Varad B, Roach M, Gottschalk AR| | View in PubMed
  42. Outcomes of hypofractionated stereotactic body radiotherapy boost for intermediate and high-risk prostate cancer.
    Anwar M, Weinberg V, Seymour Z, Hsu IJ, Roach M, Gottschalk AR| | View in PubMed
  43. Arrhythmogenic effects of mutated L-type Ca 2+-channels on an optogenetically paced muscular pump in Caenorhabditis elegans.
    Schüler C, Fischer E, Shaltiel L, Steuer Costa W, Gottschalk A| | View in PubMed
  44. Investigating the clinical advantages of a robotic linac equipped with a multileaf collimator in the treatment of brain and prostate cancer patients.
    McGuinness CM, Gottschalk AR, Lessard E, Nakamura JL, Pinnaduwage D, Pouliot J, Sims C, Descovich M| | View in PubMed
  45. Optogenetic manipulation of cGMP in cells and animals by the tightly light-regulated guanylyl-cyclase opsin CyclOp.
    Gao S, Nagpal J, Schneider MW, Kozjak-Pavlovic V, Nagel G, Gottschalk A| | View in PubMed
  46. Intraoperative Radiotherapy in the Management of Locally Recurrent Extremity Soft Tissue Sarcoma.
    Tinkle CL, Weinberg V, Braunstein SE, Wustrack R, Horvai A, Jahan T, O'Donnell RJ, Gottschalk AR| | View in PubMed
  47. Patient- and treatment-specific predictors of genitourinary function after high-dose-rate monotherapy for favorable prostate cancer.
    Raleigh DR, Chang AJ, Tomlin B, Cunha JA, Braunstein SE, Shinohara K, Gottschalk AR, Roach M, Hsu IC| | View in PubMed
  48. Obesity in regional anesthesia--a risk factor for peripheral catheter-related infections.
    Bomberg H, Albert N, Schmitt K, Gräber S, Kessler P, Steinfeldt T, Hering W, Gottschalk A, Standl T, Stork J, Meißner W, Teßmann R, Geiger P, Koch T, Spies CD, Volk T, Kubulus C| | View in PubMed
  49. AzoCholine Enables Optical Control of Alpha 7 Nicotinic Acetylcholine Receptors in Neural Networks.
    Damijonaitis A, Broichhagen J, Urushima T, Hüll K, Nagpal J, Laprell L, Schönberger M, Woodmansee DH, Rafiq A, Sumser MP, Kummer W, Gottschalk A, Trauner D| | View in PubMed
  50. Dose-volume analysis and the temporal nature of toxicity with stereotactic body radiation therapy for prostate cancer.
    Seymour ZA, Chang AJ, Zhang L, Kirby N, Descovich M, Roach M, Hsu IC, Gottschalk AR| | View in PubMed
  51. Comparison between target margins derived from 4DCT scans and real-time tumor motion tracking: insights from lung tumor patients treated with robotic radiosurgery.
    Descovich M, McGuinness C, Kannarunimit D, Chen J, Pinnaduwage D, Pouliot J, Kased N, Gottschalk AR, Yom SS| | View in PubMed
  52. Erratum: Synthetic retinal analogs modify the spectral and kinetic characteristics of microbial rhodopsin optogenetic tools.
    AzimiHashemi N, Erbguth K, Vogt A, Riemensperger T, Rauch E, Woodmansee D, Nagpal J, Brauner M, Sheves M, Fiala A, Kattner L, Trauner D, Hegemann P, Gottschalk A, Liewald JF| | View in PubMed
  53. A consistent muscle activation strategy underlies crawling and swimming in Caenorhabditis elegans.
    Butler VJ, Branicky R, Yemini E, Liewald JF, Gottschalk A, Kerr RA, Chklovskii DB, Schafer WR| | View in PubMed
  54. Microbial Rhodopsin Optogenetic Tools: Application for Analyses of Synaptic Transmission and of Neuronal Network Activity in Behavior.
    Glock C, Nagpal J, Gottschalk A| | View in PubMed
  55. Synthetic retinal analogues modify the spectral and kinetic characteristics of microbial rhodopsin optogenetic tools.
    AzimiHashemi N, Erbguth K, Vogt A, Riemensperger T, Rauch E, Woodmansee D, Nagpal J, Brauner M, Sheves M, Fiala A, Kattner L, Trauner D, Hegemann P, Gottschalk A, Liewald JF| | View in PubMed
  56. ACR appropriateness Criteria® Postradical prostatectomy irradiation in prostate cancer.
    Gustafson GS, Nguyen PL, Assimos DG, D'Amico AV, Gottschalk AR, Hsu IC, Lloyd S, Mclaughlin PW, Merrick GS, Showalter TN, Taira AV, Vapiwala N, Yamada Y, Davis BJ| | View in PubMed
  57. Analysis of dose distribution and risk of pneumonitis in stereotactic body radiation therapy for centrally located lung tumors: a comparison of robotic radiosurgery, helical tomotherapy and volumetric modulated arc therapy.
    Kannarunimit D, Descovich M, Garcia A, Chen J, Weinberg V, Mcguinness C, Pinnaduwage D, Murnane J, Gottschalk AR, Yom SS| | View in PubMed
  58. [Differences of analgesic efficacy and complication rates between ultrasound and nervestimulator guided peripheral nerve catheters : Database analysis on patient-relevant target parameters].
    Schnabel A, Middendorf B, Boschin MG, Gottschalk A, Van Aken H, Zahn PK, Pogatzki-Zahn EM| | View in PubMed
  59. Pre-plan parameters predict post-implant D90 ≥ 140 Gy for (125)I permanent prostate implants.
    Alexander J, Weinberg V, Gottschalk AR, Hsu IC, Shinohara K, Roach M| | View in PubMed
  60. ACR Appropriateness Criteria® Definitive External-Beam Irradiation in stage T1 and T2 prostate cancer.
    Nguyen PL, Aizer A, Assimos DG, D'Amico AV, Frank SJ, Gottschalk AR, Gustafson GS, Hsu IC, McLaughlin PW, Merrick G, Rosenthal SA, Showalter TN, Taira AV, Vapiwala N, Yamada Y, Davis BJ, American College of Radiology, Expert Panel on Radiation OncologyProstate| | View in PubMed
  61. Response to Drs Rogers, Hayes, and Demanes.
    Hsu IC, Yamada Y, Assimos DG, D'Amico AV, Davis BJ, Frank SJ, Gottschalk AR, Gustafson GS, McLaughlin PW, Nguyen PL, Rosenthal SA, Taira AV, Vapiwala N, Merrick G, Expert Panel on Radiation Oncology–Prostate| | View in PubMed
  62. Commentary on "A systematic review of stereotactic radiotherapy ablation for primary renal cell carcinoma." Siva S, Pham D, Gill S, Corcoran NM, Foroudi F. Division of Radiation Oncology and Cancer Imaging, Peter MacCallum Cancer Centre, Victoria, Austral
    Gottschalk A| | View in PubMed
  63. Commentary on "Patient-reported outcomes after 3-dimensional conformal, intensity-modulated, or proton beam radiotherapy for localized prostate cancer." Gray PJ, Paly JJ, Yeap BY, Sanda MG, Sandler HM, Michalski JM, Talcott JA, Coen JJ, Hamstra DA, Shiple
    Gottschalk A| | View in PubMed
  64. Commentary on "Toxicity after external beam radiotherapy for prostate cancer: an analysis of late morbidity in men with diabetes mellitus." Kalakota K, Liauw SL, Department of Radiation Oncology, Northwestern Memorial Hospital, Chicago, IL.: Urology 2013;
    Gottschalk A| | View in PubMed
  65. The Long-Term Clinical Outcomes Following Autogenous Bone Grafting for Large-Volume Defects of the Knee: 12- to 21-Year Follow-Up.
    Johnson LL, Delano M, Spector M, Pittsley A, Gottschalk A| | View in PubMed
  66. Endoscopic gold fiducial marker placement into the bladder wall to optimize radiotherapy targeting for bladder-preserving management of muscle-invasive bladder cancer: feasibility and initial outcomes.
    Garcia MM, Gottschalk AR, Brajtbord J, Konety BR, Meng MV, Roach M, Carroll PR| | View in PubMed
  67. Hypofractionated SBRT versus conventionally fractionated EBRT for prostate cancer: comparison of PSA slope and nadir.
    Anwar M, Weinberg V, Chang AJ, Hsu IC, Roach M, Gottschalk A| | View in PubMed
  68. Commentary on "secondary cancers after intensity-modulated radiotherapy, brachytherapy, and radical prostatectomy for the treatment of prostate cancer: incidence and cause-specific survival outcomes according to the initial treatment intervention." Zelefs
    Gottschalk A| | View in PubMed
  69. Evaluation of ray tracing and Monte Carlo algorithms in dose calculation and clinical outcomes for robotic stereotactic body radiotherapy of lung cancers.
    Braunstein SE, Dionisio SA, Lometti MW, Pinnaduwage DS, Chuang CF, Yom SS, Gottschalk AR, Descovich M| | View in PubMed
  70. Photoactivated adenylyl cyclases as optogenetic modulators of neuronal activity.
    Costa WS, Liewald J, Gottschalk A| | View in PubMed
  71. ACR Appropriateness Criteria high-dose-rate brachytherapy for prostate cancer.
    Hsu IC, Yamada Y, Assimos DG, D'Amico AV, Davis BJ, Frank SJ, Gottschalk AR, Gustafson GS, McLaughlin PW, Nguyen PL, Rosenthal SA, Taira AV, Vapiwala N, Merrick G| | View in PubMed
  72. Cold spot mapping inferred from MRI at time of failure predicts biopsy-proven local failure after permanent seed brachytherapy in prostate cancer patients: implications for focal salvage brachytherapy.
    Crehange G, Krishnamurthy D, Cunha JA, Pickett B, Kurhanewicz J, Hsu IC, Gottschalk AR, Shinohara K, Roach M, Pouliot J| | View in PubMed
  73. Improving plan quality and consistency by standardization of dose constraints in prostate cancer patients treated with CyberKnife.
    Descovich M, Carrara M, Morlino S, Pinnaduwage DS, Saltiel D, Pouliot J, Nash MB, Pignoli E, Valdagni R, Roach M, Gottschalk AR| | View in PubMed
  74. Sensory neuron fates are distinguished by a transcriptional switch that regulates dendrite branch stabilization.
    Smith CJ, O'Brien T, Chatzigeorgiou M, Spencer WC, Feingold-Link E, Husson SJ, Hori S, Mitani S, Gottschalk A, Schafer WR, Miller DM| | View in PubMed
  75. In vivo synaptic recovery following optogenetic hyperstimulation.
    Kittelmann M, Liewald JF, Hegermann J, Schultheis C, Brauner M, Steuer Costa W, Wabnig S, Eimer S, Gottschalk A| | View in PubMed
  76. Optogenetic manipulation of neural activity in C. elegans: from synapse to circuits and behaviour.
    Husson SJ, Gottschalk A, Leifer AM| | View in PubMed
  77. Salvage HDR brachytherapy for recurrent prostate cancer after previous definitive radiation therapy: 5-year outcomes.
    Chen CP, Weinberg V, Shinohara K, Roach M, Nash M, Gottschalk A, Chang AJ, Hsu IC| | View in PubMed
  78. Keeping track of worm trackers.
    Husson SJ, Costa WS, Schmitt C, Gottschalk A| | View in PubMed
  79. ACR Appropriateness Criteria prostate cancer--pretreatment detection, staging, and surveillance.
    Eberhardt SC, Carter S, Casalino DD, Merrick G, Frank SJ, Gottschalk AR, Leyendecker JR, Nguyen PL, Oto A, Porter C, Remer EM, Rosenthal SA| | View in PubMed
  80. Computer-assisted, atlas-based segmentation for target volume delineation in whole pelvic IMRT for prostate cancer.
    Pejavar S, Yom SS, Hwang A, Speight J, Gottschalk A, Hsu IC, Roach M, Xia P| | View in PubMed
  81. Microbial light-activatable proton pumps as neuronal inhibitors to functionally dissect neuronal networks in C. elegans.
    Husson SJ, Liewald JF, Schultheis C, Stirman JN, Lu H, Gottschalk A| | View in PubMed
  82. Can regional anaesthesia for lymph-node dissection improve the prognosis in malignant melanoma?
    Gottschalk A, Brodner G, Van Aken HK, Ellger B, Althaus S, Schulze HJ| | View in PubMed
  83. Feasibility of MR imaging/MR spectroscopy-planned focal partial salvage permanent prostate implant (PPI) for localized recurrence after initial PPI for prostate cancer.
    Hsu CC, Hsu H, Pickett B, Crehange G, Hsu IC, Dea R, Weinberg V, Gottschalk AR, Kurhanewicz J, Shinohara K, Roach M| | View in PubMed
  84. Optogenetic analysis of a nociceptor neuron and network reveals ion channels acting downstream of primary sensors.
    Husson SJ, Costa WS, Wabnig S, Stirman JN, Watson JD, Spencer WC, Akerboom J, Looger LL, Treinin M, Miller DM, Lu H, Gottschalk A| | View in PubMed
  85. Temporal compartmental dosing effects for robotic prostate stereotactic body radiotherapy.
    Shiao SL, Sahgal A, Hu W, Jabbari S, Chuang C, Descovich M, Hsu IC, Gottschalk AR, Roach M, Ma L| | View in PubMed
  86. Caenorhabditis elegans selects distinct crawling and swimming gaits via dopamine and serotonin.
    Vidal-Gadea A, Topper S, Young L, Crisp A, Kressin L, Elbel E, Maples T, Brauner M, Erbguth K, Axelrod A, Gottschalk A, Siegel D, Pierce-Shimomura JT| | View in PubMed
  87. PACα--an optogenetic tool for in vivo manipulation of cellular cAMP levels, neurotransmitter release, and behavior in Caenorhabditis elegans.
    Weissenberger S, Schultheis C, Liewald JF, Erbguth K, Nagel G, Gottschalk A| | View in PubMed
  88. Real-time multimodal optical control of neurons and muscles in freely behaving Caenorhabditis elegans.
    Stirman JN, Crane MM, Husson SJ, Wabnig S, Schultheis C, Gottschalk A, Lu H| | View in PubMed
  89. Stereotactic body radiotherapy as monotherapy or post-external beam radiotherapy boost for prostate cancer: technique, early toxicity, and PSA response.
    Jabbari S, Weinberg VK, Kaprealian T, Hsu IC, Ma L, Chuang C, Descovich M, Shiao S, Shinohara K, Roach M, Gottschalk AR| | View in PubMed
  90. Controversies in diagnosis of pulmonary embolism.
    Stein PD, Sostman HD, Dalen JE, Bailey DL, Bajc M, Goldhaber SZ, Goodman LR, Gottschalk A, Hull RD, Matta F, Pistolesi M, Tapson VF, Weg JG, Wells PS, Woodard PK, Consensus Group| | View in PubMed
  91. High-dose-rate brachytherapy boost for prostate cancer: comparison of two different fractionation schemes.
    Kaprealian T, Weinberg V, Speight JL, Gottschalk AR, Roach M, Shinohara K, Hsu IC| | View in PubMed
  92. Patellar metastatic melanoma in a 13-year-old boy.
    Burk TF, Horvai AE, Gottschalk AR, Leong SP, Kashani-Sabet M, Goldsby RE, Law J, O'Donnell RJ| | View in PubMed
  93. Gadolinium-enhanced magnetic resonance angiography for pulmonary embolism: a multicenter prospective study (PIOPED III).
    Stein PD, Chenevert TL, Fowler SE, Goodman LR, Gottschalk A, Hales CA, Hull RD, Jablonski KA, Leeper KV, Naidich DP, Sak DJ, Sostman HD, Tapson VF, Weg JG, Woodard PK, PIOPED III (Prospective Investigation of Pulmonary Embolism Diagnosis III) Investigators| | View in PubMed
  94. Comparison of patient megavoltage cone beam CT images acquired with an unflattened beam from a carbon target and a flattened treatment beam.
    Faddegon BA, Aubin M, Bani-Hashemi A, Gangadharan B, Gottschalk AR, Morin O, Sawkey D, Wu V, Yom SS| | View in PubMed
  95. A diamond target for megavoltage cone-beam CT.
    Sawkey D, Lu M, Morin O, Aubin M, Yom SS, Gottschalk AR, Bani-Hashemi A, Faddegon BA| | View in PubMed
  96. Dose gradient near target-normal structure interface for nonisocentric CyberKnife and isocentric intensity-modulated body radiotherapy for prostate cancer.
    Hossain S, Xia P, Huang K, Descovich M, Chuang C, Gottschalk AR, Roach M, Ma L| | View in PubMed
  97. Equivalent biochemical control and improved prostate-specific antigen nadir after permanent prostate seed implant brachytherapy versus high-dose three-dimensional conformal radiotherapy and high-dose conformal proton beam radiotherapy boost.
    Jabbari S, Weinberg VK, Shinohara K, Speight JL, Gottschalk AR, Hsu IC, Pickett B, McLaughlin PW, Sandler HM, Roach M| | View in PubMed
  98. [Pain and quality of life for living donors after nephrectomy].
    Gottschalk A, Götz J, Zenz M| | View in PubMed
  99. Nonrandom intrafraction target motions and general strategy for correction of spine stereotactic body radiotherapy.
    Ma L, Sahgal A, Hossain S, Chuang C, Descovich M, Huang K, Gottschalk A, Larson DA| | View in PubMed
  100. High-dose-rate brachytherapy for localized prostate adenocarcinoma post abdominoperineal resection of the rectum and pelvic irradiation: Technique and experience.
    Jabbari S, Hsu IC, Kawakami J, Weinberg VK, Speight JL, Gottschalk AR, Roach M, Shinohara K| | View in PubMed
  101. Dose recalculation and the Dose-Guided Radiation Therapy (DGRT) process using megavoltage cone-beam CT.
    Cheung J, Aubry JF, Yom SS, Gottschalk AR, Celi JC, Pouliot J| | View in PubMed
  102. Salvage permanent perineal radioactive-seed implantation for treating recurrence of localized prostate adenocarcinoma after external beam radiotherapy.
    Aaronson DS, Yamasaki I, Gottschalk A, Speight J, Hsu IC, Pickett B, Roach M, Shinohara K| | View in PubMed
  103. Correction of megavoltage cone-beam CT images of the pelvic region based on phantom measurements for dose calculation purposes.
    Aubry JF, Cheung J, Morin O, Gottschalk A, Beaulieu L, Pouliot J| | View in PubMed
  104. Intestinal signaling to GABAergic neurons regulates a rhythmic behavior in Caenorhabditis elegans.
    Mahoney TR, Luo S, Round EK, Brauner M, Gottschalk A, Thomas JH, Nonet ML| | View in PubMed
  105. Simulated real time image guided intrafraction tracking-delivery for hypofractionated prostate IMRT.
    Hossain S, Xia P, Chuang C, Verhey L, Gottschalk AR, Mu G, Ma L| | View in PubMed
  106. Sci-Thurs PM: Delivery-12: Correction and calibration of megavoltage cone-beam CT images for the calculation of the dose of the day.
    Aubry JF, Cheung J, Yom S, Gottschalk A, Aubin M, Morin O, Descovich M, Beaulieu L, Pouliot J| | View in PubMed
  107. Proposed rectal dose constraints for patients undergoing definitive whole pelvic radiotherapy for clinically localized prostate cancer.
    Chan LW, Xia P, Gottschalk AR, Akazawa M, Scala M, Pickett B, Hsu IC, Speight J, Roach M| | View in PubMed
  108. Clinical characteristics of patients with acute pulmonary embolism: data from PIOPED II.
    Stein PD, Beemath A, Matta F, Weg JG, Yusen RD, Hales CA, Hull RD, Leeper KV, Sostman HD, Tapson VF, Buckley JD, Gottschalk A, Goodman LR, Wakefied TW, Woodard PK| | View in PubMed
  109. Very low probability interpretation of V/Q lung scans in combination with low probability objective clinical assessment reliably excludes pulmonary embolism: data from PIOPED II.
    Gottschalk A, Stein PD, Sostman HD, Matta F, Beemath A| | View in PubMed
  110. Patient dose considerations for routine megavoltage cone-beam CT imaging.
    Morin O, Gillis A, Descovich M, Chen J, Aubin M, Aubry JF, Chen H, Gottschalk AR, Xia P, Pouliot J| | View in PubMed
  111. Usefulness of multidetector spiral computed tomography according to age and gender for diagnosis of acute pulmonary embolism.
    Stein PD, Beemath A, Quinn DA, Olson RE, Goodman LR, Gottschalk A, Hales CA, Hull RD, Leeper KV, Sostman HD, Weg JG, Woodard PK| | View in PubMed
  112. Daily electronic portal imaging of implanted gold seed fiducials in patients undergoing radiotherapy after radical prostatectomy.
    Schiffner DC, Gottschalk AR, Lometti M, Aubin M, Pouliot J, Speight J, Hsu IC, Shinohara K, Roach M| | View in PubMed
  113. Diagnostic pathways in acute pulmonary embolism: recommendations of the PIOPED II Investigators.
    Stein PD, Woodard PK, Weg JG, Wakefield TW, Tapson VF, Sostman HD, Sos TA, Quinn DA, Leeper KV, Hull RD, Hales CA, Gottschalk A, Goodman LR, Fowler SE, Buckley JD, PIOPED II Investigators| | View in PubMed
  114. Feasibility of high-dose-rate brachytherapy salvage for local prostate cancer recurrence after radiotherapy: the University of California-San Francisco experience.
    Lee B, Shinohara K, Weinberg V, Gottschalk AR, Pouliot J, Roach M, Hsu IC| | View in PubMed
  115. Comparative study of different concentrations of prilocaine and ropivacaine for intraoperative axillary brachial plexus block.
    Freitag M, Zbieranek K, Gottschalk A, Bubenheim M, Winter R, Tuszynski S, Standl TG| | View in PubMed
  116. Clinical outcomes of intraoperative radiation therapy for extremity sarcomas.
    Tran QN, Kim AC, Gottschalk AR, Wara WM, Phillips TL, O'donnell RJ, Weinberg V, Haas-Kogan DA| | View in PubMed
  117. Inhibition of phosphatidylinositol-3-kinase causes increased sensitivity to radiation through a PKB-dependent mechanism.
    Gottschalk AR, Doan A, Nakamura JL, Stokoe D, Haas-Kogan DA| | View in PubMed
  118. [Infratentorial progressive multifocal leukoencephalopathy in a patient with pulmonary sarcoidosis].
    Gottschalk A, Danz B, Völk M| | View in PubMed
  119. Management of isolated renal fossa recurrence following radical nephrectomy.
    Master VA, Gottschalk AR, Kane C, Carroll PR| | View in PubMed
  120. Inhibition of phosphatidylinositol-3-kinase causes cell death through a protein kinase B (PKB)-dependent mechanism and growth arrest through a PKB-independent mechanism.
    Gottschalk AR, Doan A, Nakamura JL, Haas-Kogan DA, Stokoe D| | View in PubMed
  121. PKB/Akt mediates radiosensitization by the signaling inhibitor LY294002 in human malignant gliomas.
    Nakamura JL, Karlsson A, Arvold ND, Gottschalk AR, Pieper RO, Stokoe D, Haas-Kogan DA| | View in PubMed
  122. Combined modality treatment with high-dose-rate brachytherapy boost for locally advanced prostate cancer.
    Hsu IC, Cabrera AR, Weinberg V, Speight J, Gottschalk AR, Roach M, Shinohara K| | View in PubMed
  123. High-resolution dental magnetic resonance imaging of inferior alveolar nerve responses to the extraction of third molars.
    Kress B, Gottschalk A, Anders L, Stippich C, Palm F, Bähren W, Sartor K| | View in PubMed
  124. The use of hormonal therapy with radiotherapy for prostate cancer: analysis of prospective randomised trials.
    Gottschalk AR, Roach M| | View in PubMed
  125. eat-2 and eat-18 are required for nicotinic neurotransmission in the Caenorhabditis elegans pharynx.
    McKay JP, Raizen DM, Gottschalk A, Schafer WR, Avery L| | View in PubMed
  126. Evaluation of ultrasound-based prostate localization for image-guided radiotherapy.
    Langen KM, Pouliot J, Anezinos C, Aubin M, Gottschalk AR, Hsu IC, Lowther D, Liu YM, Shinohara K, Verhey LJ, Weinberg V, Roach M| | View in PubMed
  127. Dysregulation of PTEN and protein kinase B is associated with glioma histology and patient survival.
    Ermoian RP, Furniss CS, Lamborn KR, Basila D, Berger MS, Gottschalk AR, Nicholas MK, Stokoe D, Haas-Kogan DA| | View in PubMed
  128. Bell's palsy: what is the prognostic value of measurements of signal intensity increases with contrast enhancement on MRI?
    Kress BP, Griesbeck F, Efinger K, Solbach T, Gottschalk A, Kornhuber AW, Bähren W| | View in PubMed
  129. Chronic alcohol consumption and cerebral indices of oxidative stress: is there a link?
    Götz ME, Janetzky B, Pohli S, Gottschalk A, Gsell W, Tatschner T, Ransmayr G, Leblhuber F, Gerlach M, Reichmann H, Riederer P, Böning J| | View in PubMed
  130. p27Kip1 is required for PTEN-induced G1 growth arrest.
    Gottschalk AR, Basila D, Wong M, Dean NM, Brandts CH, Stokoe D, Haas-Kogan DA| | View in PubMed
  131. Loss of PTEN facilitates HIF-1-mediated gene expression.
    Zundel W, Schindler C, Haas-Kogan D, Koong A, Kaper F, Chen E, Gottschalk AR, Ryan HE, Johnson RS, Jefferson AB, Stokoe D, Giaccia AJ| | View in PubMed
  132. Mapping of secondary somatosensory cortex activation induced by vibrational stimulation: an fMRI study.
    Maldjian JA, Gottschalk A, Patel RS, Pincus D, Detre JA, Alsop DC| | View in PubMed
  133. Anti-immunoglobulin-induced apoptosis in WEHI 231 cells involves the slow formation of ceramide from sphingomyelin and is blocked by bcl-XL.
    Wiesner DA, Kilkus JP, Gottschalk AR, Quintáns J, Dawson G| | View in PubMed
  134. Elderly Patients With no Prior Cardiopulmonary Disease Show Ventilation/Perfusion Lung Scan Characteristics That Are Sensitive and Specific for Pulmonary Embolism.
    Stein PD, Henry JW, Relyea B, Gottschalk A| | View in PubMed
  135. Pulmonary embolism among patients with a nearly normal ventilation/perfusion lung scan.
    Henry JW, Stein PD, Gottschalk A, Raskob GE| | View in PubMed
  136. Small perfusion defects in suspected pulmonary embolism.
    Stein PD, Henry JW, Gottschalk A| | View in PubMed
  137. Evaluation of individual criteria for low probability interpretation of ventilation-perfusion lung scans.
    Stein PD, Relyea B, Gottschalk A| | View in PubMed
  138. Scintigraphic lung scans and clinical assessment in critically ill patients with suspected acute pulmonary embolism.
    Henry JW, Stein PD, Gottschalk A, Relyea B, Leeper KV| | View in PubMed
  139. Apoptosis in B lymphocytes: the WEHI-231 perspective.
    Gottschalk AR, Quintáns J| | View in PubMed
  140. Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2.
    Gottschalk AR, Boise LH, Thompson CB, Quintáns J| | View in PubMed
  141. Critical review of ventilation/perfusion lung scans in acute pulmonary embolism.
    Stein PD, Gottschalk A| | View in PubMed
  142. Mechanisms of ventilatory periodicities.
    Pack AI, Gottschalk A| | View in PubMed
  143. Value of ventilation/perfusion scans versus perfusion scans alone in acute pulmonary embolism.
    Stein PD, Terrin ML, Gottschalk A, Alavi A, Henry JW| | View in PubMed
  144. Correlation between oscillations in ventilation and frequency content of the electroencephalogram.
    Pack AI, Cola MF, Goldszmidt A, Ogilvie MD, Gottschalk A| | View in PubMed
  145. Diagnosis of acute pulmonary embolism in the elderly.
    Stein PD, Gottschalk A, Saltzman HA, Terrin ML| | View in PubMed
  146. Usefulness of noninvasive diagnostic tools for diagnosis of acute pulmonary embolism in patients with a normal chest radiograph.
    Stein PD, Alavi A, Gottschalk A, Hales CA, Saltzman HA, Vreim CE, Weg JG| | View in PubMed
  147. Serial radionuclide assessment of doxorubicin cardiotoxicity in cancer patients with abnormal baseline resting left ventricular performance.
    Choi BW, Berger HJ, Schwartz PE, Alexander J, Wackers FJ, Gottschalk A, Zaret BL| | View in PubMed
  148. Tomographic gallium-67 citrate scanning. Useful new surveillance for metastatic melanoma.
    Kirkwood JM, Myers JE, Vlock DR, Neumann R, Ariyan S, Gottschalk A, Hoffer P| | View in PubMed
  149. Tomographic gallium-67 citrate scanning: useful new surveillance for metastatic melanoma.
    Kirkwood JM, Myers JE, Vlock DR, Neumann R, Ariyan S, Gottschalk A, Hoffer P| | View in PubMed
  150. Serial assessment of doxorubicin cardiotoxicity with quantitative radionuclide angiocardiography.
    Alexander J, Dainiak N, Berger HJ, Goldman L, Johnstone D, Reduto L, Duffy T, Schwartz P, Gottschalk A, Zaret BL| | View in PubMed
  151. Scintigraphic evaluation of lymphoma: a comparative study of 67Ga-citrate and 111In-Bleomycin.
    Bekerman C, Moran EM, Hoffer PB, Hendrix RW, Gottschalk A| | View in PubMed
  152. The scintillation camera with diverging collimator: physical parameters and a clinical evaluation.
    Gottschalk A, Usher MS, Turner DA, Polcyn RE, Quinn JL| | View in PubMed
  153. A COMPARISON OF RESULTS OF BRAIN SCANNING USING GA68-EDTA AND THE POSITRON SCINTILLATION CAMERA, WITH HG203-NEOHYDRIN AND THE CONVENTIONAL FOCUSED COLLIMATOR SCANNER.
    GOTTSCHALK A, MCCORMACK KR, ADAMS JE, ANGER HO| | View in PubMed
  154. RELATIVE EFFICIENCY OF HIGH-LET RADIATION (BRAGG-PEAK LITHIUM IONS) ON NORMAL RABBIT SKIN, USING INTEGRAL DOSE AS A BASIS FOR COMPARISON.
    D ANGIO GJ, LAWRENCE JH, GOTTSCHALK A, LYMAN J| | View in PubMed
  155. THE SENSITIVITY OF THE POSITRON SCINTILLATION CAMERA FOR DETECTING SIMULATED BRAIN TUMORS WITH GALLIUM 68-EDTA.
    GOTTSCHALK A, ANGER HO| | View in PubMed