Biography
Dr. Lai is also a clinical investigator with a robust research program dedicated to improving the lives of patients living with chronic liver disease and to help more of them survive to transplant and thrive after. Her research program has been continuously supported by numerous organizations including the National Institutes of Health, American Association for the Study of Liver Diseases (AASLD), American Gastroenterological Association (AGA), American College of Gastroenterology (ACG), American Society of Transplantation (AST), and American Federation for Aging Research (AFAR), in addition to the generous support of grateful patients. She serves as director of the UCSF Health Advancing Research in Clinical Hepatology (ARCH), the research arm of the UCSF Division of GI/Hepatology, as well as director of Patient-Facing Research Core of the NIH-funded UCSF Liver Center.
Dr. Lai earned her B.S. from Stanford University and combined MD/MBA degrees from Tufts University School of Medicine, then completed her clinical training in Internal Medicine at Columbia University, and gastroenterology and advanced/transplant hepatology fellowships at UCSF. Dr. Lai has received many honors for her work including the SF Business Times Top 40 under 40 Leader award, AGA Young Investigator Award in Clinical Science, AST Clinical Science Career Development Award, Young Investigator Award from the International Liver Transplantation Society, and the UCSF Department of Medicine Resident Research Award. Currently, Dr. Lai serves as an Associate Editor for the Hepatology Journal (the premier hepatology journal) and a standing member of the U.S. FDA Gastrointestinal Drug Advisory Committee.
If you are interested in contributing to Dr. Lai's research program, please consider making a tax-deductible contribution: https://makeagift.ucsf.edu/LaiResearchFund
Awards & Honors
Award | Conferred By | Date |
---|---|---|
Distinction in Mentoring (UCSF Academic Senate) | UCSF | 2023 |
Long-Term Mentor Award | UCSF Medical School | 2021 |
Young Investigator Award in Clinical Science | American Gastroenterological Association (AGA) | 2020 |
Floyd Rector Internal Medicine Research Mentoring Award | UCSF | 2019 |
Fellow | American Society of Transplantation | 2017 |
AST/Novartis Faculty Development Award (grant) | American Society of Transplantation | 2016 |
Clinical Science Career Development Award | American Society of Transplantation | 2016 |
New Investigator Award | American Geriatrics Society | 2015 |
Young Investigator Award | International Liver Transplantation Society | 2015 |
Top 40 under 40 | San Francisco Business Times | 2015 |
Paul B. Beeson Scholar in Aging Research (grant) | American Federation for Aging Research | 2014 |
Associate Scholar Genius Award (grant) | UCSF Pepper Center | 2014 |
T. Franklin Williams Scholar (grant) | Association of Specialty Professors | 2013 |
Junior Faculty Career Development Award (grant) | American College of Gastroenterology | 2012 |
Transplant Hepatology Fellowship (grant) | American Association for the Study of Liver Diseases | 2011 |
Clinical Research Award (grant) | American College of Gastrenterology | 2011 |
Vanguard Award | International Liver Transplantation Society | 2011 |
Sylvia Allison Kaplan Clinical Research Award | Northern California Kaiser Permanente | 2009 |
Alpha Omega Alpha | Tufts University School of Medicine | 2005 |
Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
UCSF | Diversity, Equity, and Inclusion Champion | 2021 | |
Columbia University Medical Center | Internship/Residency | Internal Medicine | |
Stanford University | B.S. | ||
Tufts University School of Medicine | M.D./M.B.A. | Medicine / Healthcare administration | |
UCSF | Advanced Training in Clinical Research | ||
UCSF | Fellowship in Advanced/Transplant Hepatology | ||
UCSF | Fellowship in Gastroenterology | ||
University of Louisville | Physician nutrition fellowship |
Board Certifications
American Board of Internal Medicine
American Board of Internal Medicine - Gastroenterology
Collaboration Interests
I am interested in:
- PhysicianScientist
Clinical Expertise
Alcoholic Liver Disease
Autoimmune Hepatitis
Cirrhosis
Drug-Induced Hepatitis
Fulminant Hepatic Failure
Hemochromatosis
Hepatitis B
Hepatitis C
Hepatocellular Carcinoma (Liver Cancer)
Liver Transplantation
Living Donor Liver Transplantation
Nonalcoholic Fatty Liver Disease
Polycystic Liver Disease
Primary Biliary Cirrhosis
Primary Sclerosing Cholangitis
Clinical Trials
- ALTA TIPS: A 5-year Longitudinal Observational Study of Patients Undergoing TIPS Placement (NCT03973372)Related Conditions: Cirrhosis, High Blood Pressure| Start Date: | End Date:
- Exercise Intervention in Liver Transplant Patients (NCT02367092)Related Conditions: Liver Disease, Sarcopenia, Liver Cirrhoses, Liver Transplant, Cirrhosis| Start Date: | End Date:
- Functional Assessment in Liver Transplantation (NCT03228290)Related Conditions: Liver Disease, Liver Transplant| Start Date: | End Date:
Program Affiliations
UCSF Liver Center
In the News
Grants and Funding
- The spectrum of cognitive impairment including Alzheimer’s Disease and related dementias after liver transplantation | NIH/NIA | 2023-09-15 - 2028-08-31 | Role: PI
- Investigating the role of frailty on outcomes in acutely ill patients with cirrhosis undergoing liver transplantation in the acute care setting | NIH/NIDDK | 2023-07-15 - 2028-06-30 | Role: PI
- The Impact of Frailty on Liver Transplant Outcomes in Older Adults with Hepatocellular Carcinoma | NIH/NIA | 2023-01-15 - 2027-12-31 | Role: PI
- Predicting post-transplant mortality and global functional health based on pre-transplant functional status in liver transplantation | NIH | 2018-06-15 - 2023-05-31 | Role: PI
- UCSF Liver Center | NIH | 1985-07-01 - 2023-05-31 | Role: Co-Investigator
- Development of a laboratory frailty index to improve prediction of mortality in patients with cirrhosis awaiting liver transplantation | NIH | 2020-05-01 - 2022-04-30 | Role: Principal Investigator
- Frailty and Functional Status in Older Liver Transplant Patients | NIH | 2014-09-15 - 2019-08-31 | Role: Principal Investigator
- Global Functional Status in the Older Liver Transplant Candidate | NIH | 2013-08-15 - 2015-07-31 | Role: Principal Investigator
Research Narrative
Dr. Lai has engaged in research investigating clinical outcomes in patients with chronic liver disease. Her research focuses on three main areas:
1) Understanding the impact of functional status and physiologic reserve (i.e., frailty) in patients with cirrhosis awaiting liver transplantation (actively enrolling)
2) Evaluating the association between chronic hepatitis C and systemic inflammation with Vitamin D status and bone mineral density (actively enrolling)
3) Characterizing patterns of liver allocation and distribution and their association with liver transplant outcomes (both pre- and post-transplant) on a national level
Research Interests
Impact of function status in patients on the liver-transplant waiting list
Hepatitis C virus (HCV)
Patterns of donor liver allocation and liver transplant outcomes
Publications
- Nutritional aspects of prehabilitation in adults with cirrhosis awaiting liver transplant.| | View in PubMed
- Outpatient mean arterial pressure: A potentially modifiable risk for acute kidney injury and death among cirrhosis patients.| | View in PubMed
- Quality measures in pre-liver transplant care by the Practice Metrics Committee of the American Association for the Study of Liver Diseases.| | View in PubMed
- The association between mean arterial pressure and acute kidney injury reversal among decompensated cirrhosis patients.| | View in PubMed
- Caregiver Perceptions of Social Risk Screening in Pediatric Liver Transplantation: From the Multicenter SOCIAL-Tx Study.| | View in PubMed
- Prompt Engineering for Generative Artificial Intelligence in Gastroenterology and Hepatology.| | View in PubMed
- Development of a liver disease-Specific large language model chat Interface using retrieval augmented generation.| | View in PubMed
- Applying human-centered design to the construction of a cirrhosis management clinical decision support system.| | View in PubMed
- Outcomes of High-Grade Immune Checkpoint Inhibitor Hepatitis in Hospitalized and Nonhospitalized Patients.| | View in PubMed
- A modified Hospital Frailty Risk Score for patients with cirrhosis undergoing abdominal operations.| | View in PubMed
- Financial burden following adult liver transplantation is common and associated with adverse recipient outcomes.| | View in PubMed
- Prevalence and Appropriateness of Polypharmacy in Older Adults with Inflammatory Bowel Diseases.| | View in PubMed
- Association of biological aging with frailty and post-transplant outcomes among adults with cirrhosis.| | View in PubMed
- A pragmatic tool to screen for pre-transplant cognitive impairment among potential candidates for liver transplant.| | View in PubMed
- Caregivers' and providers' perspectives of social and medical care after pediatric liver transplant: Results from the multicenter SOCIAL-Tx study.| | View in PubMed
- A Comparison of a Large Language Model vs Manual Chart Review for the Extraction of Data Elements From the Electronic Health Record.| | View in PubMed
- Prevalence of cognitive impairment in liver transplant recipients.| | View in PubMed
- Barriers and Facilitators to Exercise in Older Adults Awaiting Kidney Transplantation and Their Care Partners.| | View in PubMed
- The liver frailty index is a predictor of healthcare utilization after liver transplantation in older adults.| | View in PubMed
- Association of body mass index with post-liver transplant outcomes.| | View in PubMed
- Development of a Liver Disease-Specific Large Language Model Chat Interface using Retrieval Augmented Generation.| | View in PubMed
- Association between neighborhood-based material deprivation and liver transplant waitlist registrants demographics and mortality.| | View in PubMed
- Neighborhood Income Is Associated with Health Care Use in Pediatric Short Bowel Syndrome.| | View in PubMed
- A chair-stand time of greater than 15 seconds is associated with an increased risk of death and hospitalization in cirrhosis.| | View in PubMed
- Ambient air pollution is associated with graft failure/death in pediatric liver transplant recipients.| | View in PubMed
- Association of state Medicaid expansion policies with pediatric liver transplant outcomes.| | View in PubMed
- Nonselective beta-blockers may lead to stage 2 acute kidney injury and waitlist mortality in child class C cirrhosis.| | View in PubMed
- Variation in skeletal muscle mass among patients with cirrhosis of different self-identified race/ethnicity.| | View in PubMed
- Structured Moderate Exercise and Biomarkers of Kidney Health in Sedentary Older Adults: The Lifestyle Interventions and Independence for Elders Randomized Clinical Trial.| | View in PubMed
- A comparison of large language model versus manual chart review for extraction of data elements from the electronic health record.| | View in PubMed
- Systematic Review and Meta-Analysis of Brief Cognitive Instruments to Evaluate Suspected Dementia in Chinese-Speaking Populations.| | View in PubMed
- Predicting post-liver transplant outcomes in patients with acute-on-chronic liver failure using Expert-Augmented Machine Learning.| | View in PubMed
- Clinical decision support and electronic interventions to improve care quality in chronic liver diseases and cirrhosis.| | View in PubMed
- Racial and Ethnic Disparities Among Patients Hospitalized for Acute Cholangitis in the United States.| | View in PubMed
- Brief PROMIS Assessment Screens for Frailty and Predicts Hospitalizations in Liver Transplant Candidates.| | View in PubMed
- Reply: What is the actual role of decompensated cirrhosis in the breakthrough SARS-CoV-2 infection?| | View in PubMed
- Novel autoantibody targets identified in patients with autoimmune hepatitis (AIH) by PhIP-Seq reveals pathogenic insights.| | View in PubMed
- Caregiver Burden in Adult Solid Organ Transplantation.| | View in PubMed
- Clinical Characteristics Associated With Posttransplant Survival Among Adults 70 Years Old or Older Undergoing Liver Transplantation.| | View in PubMed
- Time to embrace PROMIS-29 as the standard health-related quality of life instrument for patients with cirrhosis.| | View in PubMed
- Early Liver Specialist Consultation is Associated With Faster Biochemical Resolution of Severe Immune Checkpoint Inhibitor-Induced Hepatitis.| | View in PubMed
- Targets and study design for symptom-focused trials aimed at patients with cirrhosis: An expert consensus.| | View in PubMed
- Change in Platelet Count after Transjugular Intrahepatic Portosystemic Shunt Creation: An Advancing Liver Therapeutic Approaches (ALTA) Group Study.| | View in PubMed
- Actionable Solutions to Achieve Health Equity in Chronic Liver Disease.| | View in PubMed
- The tele-liver frailty index (TeLeFI): development of a novel frailty tool in patients with cirrhosis via telemedicine.| | View in PubMed
- Artificial intelligence-based text generators in hepatology: ChatGPT is just the beginning.| | View in PubMed
- Serum and plasma protein biomarkers associated with frailty in patients with cirrhosis.| | View in PubMed
- Breakthrough SARS-CoV-2 infection outcomes in vaccinated patients with chronic liver disease and cirrhosis: A National COVID Cohort Collaborative study.| | View in PubMed
- Women with cirrhosis have lower self-rated health than men.| | View in PubMed
- Association of Frailty With Health-Related Quality of Life in Liver Transplant Recipients.| | View in PubMed
- Promoting Prognostic Understanding and Health Equity for Patients With Advanced Liver Disease: Using "Best Case/Worst Case".| | View in PubMed
- Promoting Prognostic Understanding and Health Equity for Patients With Advanced Liver Disease: Using "Best Case/Worst Case".| | View in PubMed
- The impact of right atrial pressure on outcomes in patients undergoing TIPS, an ALTA group study.| | View in PubMed
- Introducing Norah Terrault, MD, MPH, Our 2023 AASLD President.| | View in PubMed
- Addressing sex-based disparities in solid organ transplantation in the United States - a conference report.| | View in PubMed
- CT-quantified sarcopenic visceral obesity is associated with poor transplant waitlist mortality in patients with cirrhosis.| | View in PubMed
- Cirrhosis Inpatients Receive More Opioids and Fewer Nonopioid Analgesics Than Patients Without Cirrhosis.| | View in PubMed
- Multicenter assessment of hypertension management among liver transplantation recipients.| | View in PubMed
- Response to: "Towards optimally replacing the current version of MELD".| | View in PubMed
- Predictors of Length of Stay and Mortality During Simultaneous Liver-Kidney Transplant Index Admission: Results From the US-Multicenter SLKT Consortium.| | View in PubMed
- Role of Oral Health, Frailty, and Minimal Hepatic Encephalopathy in the Risk of Hospitalization: A Prospective Multi-Center Cohort of Outpatients With Cirrhosis.| | View in PubMed
- Factors associated with cardiovascular events after simultaneous liver-kidney transplant from the US Multicenter Simultaneous Liver-Kidney Transplant Consortium.| | View in PubMed
- Understanding Current Limitations to Exercise Interventions After Liver Transplantation.| | View in PubMed
- Which preoperative assessment modalities best identify patients who are suitable for enhanced recovery after liver transplantation? A systematic review of the literature and expert panel recommendations.| | View in PubMed
- Personality Traits in Patients With Cirrhosis Are Different From Those of the General Population and Impact Likelihood of Liver Transplantation.| | View in PubMed
- Leveraging a New ICD-10 Diagnosis Code to Characterize Hospitalized Patients With Primary Sclerosing Cholangitis.| | View in PubMed
- Association of serum metabolites and gut microbiota at hospital admission with nosocomial infection development in patients with cirrhosis.| | View in PubMed
- Novel approaches are needed to study social determinants of health in liver transplantation.| | View in PubMed
- Medical Need and Transplant Accessibility-Reply.| | View in PubMed
- Hepatic and renal function impact concentrations of plasma biomarkers of neuropathology.| | View in PubMed
- Breakthrough SARS-CoV-2 Infection Outcomes in Vaccinated Patients with Chronic Liver Disease and Cirrhosis: A National COVID Cohort Collaborative Study.| | View in PubMed
- Financial burden in adults with chronic liver disease: A scoping review.| | View in PubMed
- Burden of early hospitalization after simultaneous liver-kidney transplantation: Results from the US Multicenter SLKT Consortium.| | View in PubMed
- The digital determinants of liver disease.| | View in PubMed
- Caregiver perspectives on the everyday medical and social needs of long-term pediatric liver transplant patients.| | View in PubMed
- "Beyond MELD" - Emerging strategies and technologies for improving mortality prediction, organ allocation and outcomes in liver transplantation.| | View in PubMed
- Conceptualizing a Traditional Chinese Medicine and Pathology of Arousal Diagnostic and Pathophysiological Framework for Postacute Sequelae of COVID-19.| | View in PubMed
- Improvement in Long-COVID Symptoms Using Acupuncture: A Case Study.| | View in PubMed
- Sarcopenic visceral obesity is associated with increased post-liver transplant mortality in acutely ill patients with cirrhosis.| | View in PubMed
- Loneliness in adults awaiting liver transplantation at 7 U.S. transplant centers.| | View in PubMed
- A review of racial, socioeconomic, and geographic disparities in pediatric liver transplantation.| | View in PubMed
- Medical Need, Financial Resources, and Transplant Accessibility.| | View in PubMed
- Admission Serum Metabolites and Thyroxine Predict Advanced Hepatic Encephalopathy in a Multicenter Inpatient Cirrhosis Cohort.| | View in PubMed
- Variability in serum creatinine is associated with waitlist and post-liver transplant mortality in patients with cirrhosis.| | View in PubMed
- Improving the Model for End-Stage Liver Disease with sodium by incorporating kidney dysfunction types.| | View in PubMed
- The bidirectional relationship between nonalcoholic fatty liver disease and sarcopenia.| | View in PubMed
- Acute-on-Chronic Liver Failure.| | View in PubMed
- Association of Primary Care Shortage Areas with Adverse Outcomes after Pediatric Liver Transplant.| | View in PubMed
- Perioperative Delta Sodium and Post-Liver Transplant Neurological Complications in Liver Transplant Recipients.| | View in PubMed
- Top Ten Tips Palliative Care Clinicians Should Know About Solid Organ Transplantation.| | View in PubMed
- Osmotic Demyelination Syndrome in Hospitalized Patients With Cirrhosis: Analysis of the National Inpatient Sample (NIS).| | View in PubMed
- Implicit bias and the gender inequity in liver transplantation.| | View in PubMed
- Acute-on-Chronic Liver Failure Clinical Guidelines.| | View in PubMed
- Prognosis of hospitalized patients with cirrhosis and acute kidney disease.| | View in PubMed
- Reply.| | View in PubMed
- Long-Term Opioid Use Among Veterans with Cirrhosis: High-Dose Prescriptions in an Exceedingly High-Risk Population.| | View in PubMed
- The 5Ms of Geriatrics in Gastroenterology: The Path to Creating Age-Friendly Care for Older Adults With Inflammatory Bowel Diseases and Cirrhosis.| | View in PubMed
- Frailty, mortality, and health care utilization after liver transplantation: From the Multicenter Functional Assessment in Liver Transplantation (FrAILT) Study.| | View in PubMed
- Racial/ethnic disparities in wait-list outcomes are only partly explained by socioeconomic deprivation among children awaiting liver transplantation.| | View in PubMed
- Frailty is associated with increased risk of cirrhosis disease progression and death.| | View in PubMed
- Frailty is strongly associated with self-reported symptom burden among patients with cirrhosis.| | View in PubMed
- An Analysis of Free-Text Refusals as an Indicator of Readiness to Accept Organ Offers in Liver Transplantation.| | View in PubMed
- The Prediction of In-Hospital Mortality in Decompensated Cirrhosis with Acute-on-Chronic Liver Failure.| | View in PubMed
- Sex-based Disparities in Hepatocellular Carcinoma Recurrence After Liver Transplantation.| | View in PubMed
- Pilot Randomized Controlled Trial of an Advance Care Planning Video Decision Tool for Patients With Advanced Liver Disease.| | View in PubMed
- Frailty and the Risk of Acute Kidney Injury Among Patients With Cirrhosis.| | View in PubMed
- Frailty and Risk of Serious Infections in Biologic-treated Patients With Inflammatory Bowel Diseases.| | View in PubMed
- Addressing Social Adversity to Improve Outcomes for Children After Liver Transplant.| | View in PubMed
- Outcomes After TIPS for Ascites and Variceal Bleeding in a Contemporary Era-An ALTA Group Study.| | View in PubMed
- Thinking Ahead: Advance Care Planning for Patients With Cirrhosis.| | View in PubMed
- Malnutrition, Frailty, and Sarcopenia in Patients With Cirrhosis: 2021 Practice Guidance by the American Association for the Study of Liver Diseases.| | View in PubMed
- Correcting the sex disparity in access to liver transplantation: Lest perfect be the enemy of better.| | View in PubMed
- Cognitive Impairment and Physical Frailty in Patients With Cirrhosis.| | View in PubMed
- Temporal Trends and Evolving Outcomes After Simultaneous Liver-Kidney Transplantation: Results from the US SLKT Consortium.| | View in PubMed
- Symptom Burden Is Associated with Increased Emergency Department Utilization among Patients with Cirrhosis.| | View in PubMed
- Inpatient Frailty Assessment Is Feasible and Predicts Nonhome Discharge and Mortality in Decompensated Cirrhosis.| | View in PubMed
- Association Between Kidney Dysfunction Types and Mortality Among Hospitalized Patients with Cirrhosis.| | View in PubMed
- Outcomes of SARS-CoV-2 Infection in Patients With Chronic Liver Disease and Cirrhosis: A National COVID Cohort Collaborative Study.| | View in PubMed
- The relationship between frailty and cirrhosis etiology: From the Functional Assessment in Liver Transplantation (FrAILT) Study.| | View in PubMed
- Admission Urinary and Serum Metabolites Predict Renal Outcomes in Hospitalized Patients With Cirrhosis.| | View in PubMed
- Sarcopenia and frailty in decompensated cirrhosis.| | View in PubMed
- Developing Priorities for Palliative Care Research in Advanced Liver Disease: A Multidisciplinary Approach.| | View in PubMed
- Visceral Adipose Tissue Inflammation and Radiographic Visceral-to-Subcutaneous Adipose Tissue Ratio in Patients with Cirrhosis.| | View in PubMed
- Outcomes of SARS-CoV-2 Infection in Patients with Chronic Liver Disease and Cirrhosis: a N3C Study.| | View in PubMed
- Association of Cognitive Function Screening Results with Adherence and Performance in a Pedometer-Based Intervention.| | View in PubMed
- Advance Care Planning in Liver Transplant-Preparing for Both Life and Death.| | View in PubMed
- Renal Outcomes After Simultaneous Liver-Kidney Transplantation: Results from the US Multicenter Simultaneous Liver-Kidney Transplantation Consortium.| | View in PubMed
- A Multicenter Pilot Randomized Clinical Trial of a Home-Based Exercise Program for Patients With Cirrhosis: The Strength Training Intervention (STRIVE).| | View in PubMed
- Early Kidney Allograft Failure After Simultaneous Liver-kidney Transplantation: Evidence for Utilization of the Safety Net?| | View in PubMed
- Patterns of Inpatient Opioid Use and Related Adverse Events Among Patients With Cirrhosis: A Propensity-Matched Analysis.| | View in PubMed
- A Methodology to Generate Longitudinally Updated Acute-On-Chronic Liver Failure Prognostication Scores From Electronic Health Record Data.| | View in PubMed
- Center variation in long-term outcomes for socioeconomically deprived children.| | View in PubMed
- Renal Recovery and Mortality Risk among Patients with Hepatorenal Syndrome Receiving Chronic Maintenance Dialysis.| | View in PubMed
- Association of Frailty and Sex With Wait List Mortality in Liver Transplant Candidates in the Multicenter Functional Assessment in Liver Transplantation (FrAILT) Study.| | View in PubMed
- Assessment of the Frail Patient With End-Stage Liver Disease: A Practical Overview of Sarcopenia, Physical Function, and Disability.| | View in PubMed
- Implementing a Height-Based Rule for the Allocation of Pediatric Donor Livers to Adults: A Liver Simulated Allocation Model Study.| | View in PubMed
- Low Predictability of Readmissions and Death Using Machine Learning in Cirrhosis.| | View in PubMed
- Evaluating the Associations Between the Liver Frailty Index and Karnofsky Performance Status With Waitlist Mortality.| | View in PubMed
- National Early Career Transplant Hepatologist Survey: Compensation, Burnout, and Job Satisfaction.| | View in PubMed
- Nonalcoholic Fatty Liver Disease and Diabetes Mellitus Are Associated With Post-Transjugular Intrahepatic Portosystemic Shunt Renal Dysfunction: An Advancing Liver Therapeutic Approaches Group Study.| | View in PubMed
- Increased Risk of ACLF and Inpatient Mortality in Hospitalized Patients with Cirrhosis and Hepatic Hydrothorax.| | View in PubMed
- Kefir Peptides Prevent Estrogen Deficiency-Induced Bone Loss and Modulate the Structure of the Gut Microbiota in Ovariectomized Mice.| | View in PubMed
- Identifying an Optimal Liver Frailty Index Cutoff to Predict Waitlist Mortality in Liver Transplant Candidates.| | View in PubMed
- Outcomes of Liver Transplantation Among Older Recipients With Nonalcoholic Steatohepatitis in a Large Multicenter US Cohort: the Re-Evaluating Age Limits in Transplantation Consortium.| | View in PubMed
- Unforeseen consequences of the COVID pandemic.| | View in PubMed
- Progression of Stage 2 and 3 Acute Kidney Injury in Patients With Decompensated Cirrhosis and Ascites.| | View in PubMed
- Neighborhood socioeconomic deprivation, racial segregation, and organ donation across 5 states.| | View in PubMed
- Association of motivations and barriers with participation and performance in a pedometer-based intervention.| | View in PubMed
- Psychological contributors to the frail phenotype: The association between resilience and frailty in patients with cirrhosis.| | View in PubMed
- Serum Levels of Metabolites Produced by Intestinal Microbes and Lipid Moieties Independently Associated With Acute-on-Chronic Liver Failure and Death in Patients With Cirrhosis.| | View in PubMed
- Time for Action to Address the Persistent Sex-Based Disparity in Liver Transplant Access.| | View in PubMed
- Frailty as an Immune-Mediated Condition That Leads to an Increased Risk of Acute Cellular Rejection in Liver Transplant Recipients.| | View in PubMed
- Liver Transplant Survivorship.| | View in PubMed
- Low Rates of Advance Care Planning (ACP) Discussions Despite Readiness to Engage in ACP Among Liver Transplant Candidates.| | View in PubMed
- Multicenter Study of Age, Frailty, and Waitlist Mortality Among Liver Transplant Candidates.| | View in PubMed
- Aggressive utilization of liver allografts: Improved outcomes over time.| | View in PubMed
- Women who undergo liver transplant have longer length of stay post-transplant compared with men.| | View in PubMed
- Insurance Status But Not Race and Ethnicity Are Associated With Outcomes in a Large Hospitalized Cohort of Patients With Cirrhosis.| | View in PubMed
- Physical Function, Physical Activity, and Quality of Life After Liver Transplantation.| | View in PubMed
- Association of Karnofsky Performance Status with waitlist mortality among older and younger adults awaiting kidney transplantation.| | View in PubMed
- Chronic Kidney Disease in Liver Transplant Candidates: A Rising Burden Impacting Post-Liver Transplant Outcomes.| | View in PubMed
- Changes in frailty are associated with waitlist mortality in patients with cirrhosis.| | View in PubMed
- Effect of a pedometer-based walking intervention on body composition in patients with ESRD: a randomized controlled trial.| | View in PubMed
- Underutilization of Hospice in Inpatients with Cirrhosis: The NACSELD Experience.| | View in PubMed
- Neighborhood socioeconomic deprivation is associated with worse patient and graft survival following pediatric liver transplantation.| | View in PubMed
- Frailty Is Associated With Increased Rates of Acute Cellular Rejection Within 3 Months After Liver Transplantation.| | View in PubMed
- A Comprehensive Review of Outcome Predictors in Low MELD Patients.| | View in PubMed
- Response to "Reply to: 'The decreasing predictive power of MELD in an era of changing etiology of liver disease'".| | View in PubMed
- Gender Differences Among Patients Hospitalized With Cirrhosis in the United States.| | View in PubMed
- Split liver transplantation is utilized infrequently and concentrated at few transplant centers in the United States.| | View in PubMed
- Association Between Liver Transplant Wait-list Mortality and Frailty Based on Body Mass Index.| | View in PubMed
- Sex Differences in the Association Between Frailty and Sarcopenia in Patients With Cirrhosis.| | View in PubMed
- Differential Impact of Age Among Liver Transplant Candidates With and Without Hepatocellular Carcinoma.| | View in PubMed
- Identifying a clinically relevant cutoff for height that is associated with a higher risk of waitlist mortality in liver transplant candidates.| | View in PubMed
- Sarcopenia Predicts Post-transplant Mortality in Acutely Ill Men Undergoing Urgent Evaluation and Liver Transplantation.| | View in PubMed
- Frailty and the Burden of Concurrent and Incident Disability in Patients With Cirrhosis: A Prospective Cohort Study.| | View in PubMed
- Hospitalized Women With Cirrhosis Have More Nonhepatic Comorbidities and Associated Complications Than Men.| | View in PubMed
- Review article: impact of exercise on physical frailty in patients with chronic liver disease.| | View in PubMed
- The decreasing predictive power of MELD in an era of changing etiology of liver disease.| | View in PubMed
- A North American Expert Opinion Statement on Sarcopenia in Liver Transplantation.| | View in PubMed
- Barriers to ideal outcomes after pediatric liver transplantation.| | View in PubMed
- Nosocomial Infections Are Frequent and Negatively Impact Outcomes in Hospitalized Patients With Cirrhosis.| | View in PubMed
- Impact of Muscle Gain after Transjugular Intrahepatic Portosystemic Shunt Creation on Patients Awaiting Liver Transplantation.| | View in PubMed
- Frailty in liver transplantation: An expert opinion statement from the American Society of Transplantation Liver and Intestinal Community of Practice.| | View in PubMed
- Changes in Simultaneous Liver-kidney Transplant Allocation Policy May Impact Postliver Transplant Outcomes.| | View in PubMed
- Split-Liver Allocation: An Underused Opportunity to Expand Access to Liver Transplantation.| | View in PubMed
- Targets to improve quality of care for patients with hepatic encephalopathy: data from a multi-centre cohort.| | View in PubMed
- The Range and Reproducibility of the Liver Frailty Index.| | View in PubMed
- Impact of Chronic Kidney Disease on Outcomes in Cirrhosis.| | View in PubMed
- Outcomes in Patients With Cirrhosis on Primary Compared to Secondary Prophylaxis for Spontaneous Bacterial Peritonitis.| | View in PubMed
- Outcomes After Listing for Liver Transplant in Patients With Acute-on-Chronic Liver Failure: The Multicenter North American Consortium for the Study of End-Stage Liver Disease Experience.| | View in PubMed
- Women on the liver transplantation waitlist are at increased risk of hospitalization compared to men.| | View in PubMed
- Deceased Pediatric Donor Livers: How Current Policy Drives Allocation and Transplantation.| | View in PubMed
- Association Between Renal Function Pattern and Mortality in Patients With Cirrhosis.| | View in PubMed
- Frailty Associated With Waitlist Mortality Independent of Ascites and Hepatic Encephalopathy in a Multicenter Study.| | View in PubMed
- Functional status at listing predicts waitlist and posttransplant mortality in pediatric liver transplant candidates.| | View in PubMed
- Report from the American Society of Transplantation on frailty in solid organ transplantation.| | View in PubMed
- Sex hormone levels by presence and severity of cirrhosis in women with chronic hepatitis C virus infection.| | View in PubMed
- How I Approach It: Improving Nutritional Status in Patients With Cirrhosis.| | View in PubMed
- Poor performance of psoas muscle index for identification of patients with higher waitlist mortality risk in cirrhosis.| | View in PubMed
- Acute-on-Chronic Liver Failure: Getting Ready for Prime Time?| | View in PubMed
- Beta-blockers and physical frailty in patients with end-stage liver disease.| | View in PubMed
- Patient and Caregiver Attitudes and Practices of Exercise in Candidates Listed for Liver Transplantation.| | View in PubMed
- Determination of Free 25(OH)D Concentrations and Their Relationships to Total 25(OH)D in Multiple Clinical Populations.| | View in PubMed
- Association Between Intestinal Microbiota Collected at Hospital Admission and Outcomes of Patients With Cirrhosis.| | View in PubMed
- People who experience seclusion in adult mental health inpatient services: An examination of health of the nation outcome scales scores.| | View in PubMed
- "Normal" Creatinine Levels Predict Persistent Kidney Injury and Waitlist Mortality in Outpatients With Cirrhosis.| | View in PubMed
- The Impact of Albumin Use on Resolution of Hyponatremia in Hospitalized Patients With Cirrhosis.| | View in PubMed
- Receipt of a pediatric liver offer as the first offer reduces waitlist mortality for adult women.| | View in PubMed
- Assessment of the spectrum of hepatic encephalopathy: A multicenter study.| | View in PubMed
- Reply.| | View in PubMed
- NACSELD acute-on-chronic liver failure (NACSELD-ACLF) score predicts 30-day survival in hospitalized patients with cirrhosis.| | View in PubMed
- Physical frailty after liver transplantation.| | View in PubMed
- Association of Cardiac Abnormalities to the Frail Phenotype in Cirrhotic Patients on the Waitlist: From the Functional Assessment in Liver Transplantation Study.| | View in PubMed
- Primary healthcare utilisation among adults with mood and anxiety disorders: an analysis of the New Zealand Health Survey.| | View in PubMed
- A2 liver transplantation across the ABO barrier: Increasing options in the donor pool?| | View in PubMed
- Sex-based disparities in delisting for being "too sick" for liver transplantation.| | View in PubMed
- Prediction of Fungal Infection Development and Their Impact on Survival Using the NACSELD Cohort.| | View in PubMed
- The Liver Frailty Index Improves Mortality Prediction of the Subjective Clinician Assessment in Patients With Cirrhosis.| | View in PubMed
- Opioid and opioid substitution therapy in liver transplant candidates: A survey of center policies and practices.| | View in PubMed
- Liver Transplantation in the Obese Cirrhotic Patient.| | View in PubMed
- Transplant for the very sick: No limitations in donor quality?| | View in PubMed
- Analysis of Liver Offers to Pediatric Candidates on the Transplant Wait List.| | View in PubMed
- Development of a novel frailty index to predict mortality in patients with end-stage liver disease.| | View in PubMed
- Race/ethnicity is associated with ABO-nonidentical liver transplantation in the United States.| | View in PubMed
- Reporting functional status in UNOS: The weakness of the Karnofsky Performance Status Scale.| | View in PubMed
- A multicenter study to define sarcopenia in patients with end-stage liver disease.| | View in PubMed
- Cost-Effectiveness of Direct-Acting Antiviral Treatment in Hepatitis C-Infected Liver Transplant Candidates With Compensated Cirrhosis and Hepatocellular Carcinoma.| | View in PubMed
- Disability in patients with end-stage liver disease: Results from the functional assessment in liver transplantation study.| | View in PubMed
- Frailty is independently associated with increased hospitalisation days in patients on the liver transplant waitlist.| | View in PubMed
- A framework to determine when liver transplantation is futile.| | View in PubMed
- Clinical Liver Disease| View in PubMed
- Short Physical Performance Battery and all-cause mortality: systematic review and meta-analysis.| | View in PubMed
- Factors Associated with Medication Non-adherence in Patients with End-Stage Liver Disease.| | View in PubMed
- Editorial: Advancing Adoption of Frailty to Improve the Care of Patients with Cirrhosis: Time for a Consensus on a Frailty Index.| | View in PubMed
- Performance-Based Measures Associate With Frailty in Patients With End-Stage Liver Disease.| | View in PubMed
- Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy.| | View in PubMed
- Hepatic Encephalopathy Is Associated With Mortality in Patients With Cirrhosis Independent of Other Extrahepatic Organ Failures.| | View in PubMed
- Underutilization of palliative care services in the liver transplant population.| | View in PubMed
- A Comparison of Muscle Function, Mass, and Quality in Liver Transplant Candidates: Results From the Functional Assessment in Liver Transplantation Study.| | View in PubMed
- ABO-Nonidentical Liver Transplantation in the United States.| | View in PubMed
- Defining the threshold for too sick for transplant.| | View in PubMed
- Response to clinical assessments of health status as a potential marker to identify patients who are too sick to undergo transplantation.| | View in PubMed
- Functional decline in patients with cirrhosis awaiting liver transplantation: Results from the functional assessment in liver transplantation (FrAILT) study.| | View in PubMed
- Functional impairment in older liver transplantation candidates: From the functional assessment in liver transplantation study.| | View in PubMed
- Outcomes for liver transplant candidates listed with low model for end-stage liver disease score.| | View in PubMed
- Kidney Failure and Liver Allocation: Current Practices and Potential Improvements.| | View in PubMed
- Decision support for organ offers in liver transplantation.| | View in PubMed
- Hepatitis C genotype influences post-liver transplant outcomes.| | View in PubMed
- Total 25(OH) vitamin D, free 25(OH) vitamin D and markers of bone turnover in cirrhotics with and without synthetic dysfunction.| | View in PubMed
- Clinician assessments of health status predict mortality in patients with end-stage liver disease awaiting liver transplantation.| | View in PubMed
- Bone Mineral Density, Bone Turnover, and Systemic Inflammation in Non-cirrhotics with Chronic Hepatitis C.| | View in PubMed
- Role of delta-aminolevulinic acid in the symptoms of acute porphyria.| | View in PubMed
- Combined effects of recipient age and model for end-stage liver disease score on liver transplantation outcomes.| | View in PubMed
- The octogenarian donor: can the liver be "younger than stated age"?| | View in PubMed
- Expanded criteria donors.| | View in PubMed
- Frailty predicts waitlist mortality in liver transplant candidates.| | View in PubMed
- A comparison of measured and calculated free 25(OH) vitamin D levels in clinical populations.| | View in PubMed
- Variability in free 25(OH) vitamin D levels in clinical populations.| | View in PubMed
- Reducing infection transmission in solid organ transplantation through donor nucleic acid testing: a cost-effectiveness analysis.| | View in PubMed
- Offer patterns of nationally placed livers by donation service area.| | View in PubMed
- Center competition and outcomes following liver transplantation.| | View in PubMed
- Sudden onset vision loss in an 8-year-old female with McCune-Albright syndrome.| | View in PubMed
- An examination of liver offers to candidates on the liver transplant wait-list.| | View in PubMed
- Recipient-donor race mismatch for African American liver transplant patients with chronic hepatitis C.| | View in PubMed
- Risk of advanced fibrosis with grafts from hepatitis C antibody-positive donors: a multicenter cohort study.| | View in PubMed
- Effects of ethnicity and socioeconomic status on survival and severity of fibrosis in liver transplant recipients with hepatitis C virus.| | View in PubMed
- Patient, center and geographic characteristics of nationally placed livers.| | View in PubMed
- Hepatic steatosis at 1 year is an additional predictor of subsequent fibrosis severity in liver transplant recipients with recurrent hepatitis C virus.| | View in PubMed
- Hepatitis C virus-infected women have a higher risk of advanced fibrosis and graft loss after liver transplantation than men.| | View in PubMed
- Gender differences in liver donor quality are predictive of graft loss.| | View in PubMed
- Height contributes to the gender difference in wait-list mortality under the MELD-based liver allocation system.| | View in PubMed
- Lessons from HIV therapy applied to viral hepatitis therapy: summary of a workshop.| | View in PubMed
- A novel housestaff educational model for quaternary-care patients at an academic health center.| | View in PubMed
- Resource utilization of living donor versus deceased donor liver transplantation is similar at an experienced transplant center.| | View in PubMed